Results 51 to 60 of about 2,590 (171)

Randomized, single‐centre, double‐blinded repeated dose investigation of safety and tolerability of ocular administrations of a novel silica eye drop product in healthy volunteers

Acta Ophthalmologica, Volume 104, Issue 5, Page 572-579, August 2026.
Abstract Purpose Managing ocular diseases often requires frequent eye drop administration, which can challenge patient compliance. A long‐acting eye drop technology using an amorphous synthetic silica composite was developed to address this. Our study aimed to assess the safety and tolerability of the Silica Eye Drop platform in healthy volunteers over
Aleksandra Poluianova, Marceline N. Akieh‐Pirkanniemi, Arto Hartikainen, Hanna Arstila, Kai Kaarniranta, Lasse Leino   +5 more
wiley   +1 more source

Fecal microbiota transplantation for glaucoma; a potential emerging treatment strategy

Current Research in Microbial Sciences
Glaucoma is the primary cause of irreversible blindness globally. Different glaucoma subtypes are identified by their underlying mechanisms, and treatment options differ by its pathogenesis.
Rasoul Ebrahimi, Yeganeh Farsi, Seyed Aria Nejadghaderi   +2 more
doaj   +1 more source

Outcomes and complications of sponges versus tires for scleral buckling in primary rhegmatogenous retinal detachment: The Manchester Buckle Study

Acta Ophthalmologica, Volume 104, Issue 5, Page e538-e543, August 2026.
Abstract Purpose To compare preoperative characteristics and postoperative anatomical and functional outcomes of scleral buckle surgery using sponges versus tires, as well as explant‐related complications and the frequency of explant removal. Methods This retrospective study included patients with primary rhegmatogenous retinal detachment (RRD) who ...
Peter Kiraly, Myrta Lippera, Naseer Ally, Ritu Agarwal, George Moussa, Tsveta Ivanova, Felipe Dhawahir‐Scala, Niall Patton, George Turner, Stephen Charles, Assad Jalil, Kirti M. Jasani   +11 more
wiley   +1 more source

A novel bilayered expanded polytetrafluoroethylene glaucoma implant creates a permeable thin capsule independent of aqueous humor exposure

Bioengineering & Translational Medicine, 2021
The purpose of these studies was to evaluate clinical, functional, and histopathological features of glaucoma drainage implants (GDIs) fabricated from novel, custom‐tailored expanded polytetrafluoroethylene (ePTFE).
Amanda Kiely Bicket, Julia Szeto, Peter Roeber, Jeff Towler, Mitch Troutman, E. Randy Craven, Anup Khatana, Ike Ahmed, Harry Quigley, Pradeep Ramulu, Ian F. Pitha   +10 more
doaj   +1 more source

Safety considerations of gene‐based therapies for Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract Gene‐based therapies show increasing promise for the treatment of neurologic disease. In 2016, nusinersen, an RNA‐based therapy, was approved for children with spinal muscular atrophy (SMA). Over 200 clinical trials have utilized gene therapy approaches for a host of neurodegenerative and neuromuscular disorders, including Alzheimer's disease (
Elizabeth A. Bevins, Gabriel C. Léger, Michelle A. Herman, John M. Ringman, Subhojit Roy, Matthew Shtrahman, Judy Pa, Howard H. Feldman   +7 more
wiley   +1 more source

Late-Onset Endophthalmitis Secondary to Exposed Glaucoma Tube Implant in a Rare Case of Paediatric Glaucoma

Case Reports in Ophthalmological Medicine, 2011
Glaucoma drainage implants (GDIs) are used to treat paediatric glaucoma resistant to conventional medical and surgical treatment, achieving good intraocular pressure (IOP) control and long-term success.
Akshatha Ranganath, Adnan Hashim
doaj   +1 more source

Toward Wireless Implantable Robotic Systems Driven by Magnetic Field for Personalized Therapy

Advanced Robotics Research, Volume 2, Issue 3, June 2026.
Robotic materials are playing an increasingly vital role in enabling sensing and actuation at small scales. This perspective highlights recent advances in magnetic materials and magnetically actuated devices for wireless sensing, actuation, and energy harvesting toward implantable robotic systems for closed‐loop therapy.
Yusheng Wang, Ruijian Ge, Xiaoguang Dong
wiley   +1 more source

Advancing Flexible Pressure Sensors for Next‐Generation Medical Monitoring

Advanced Sensor Research, Volume 5, Issue 6, June 2026.
This review highlights recent advances in flexible pressure sensors for next‐generation medical monitoring. The sensing mechanisms, material and structural optimization strategies, and intelligent algorithms are systematically summarized. Emerging applications in cardiovascular, respiratory, neurological, laryngeal, and ocular disease monitoring are ...
Chunjun Su, Xingfa Gao, Rixuan Wang, Shuhua Yang, Yinglun Sun   +4 more
wiley   +1 more source

Glaucoma Drainage Implants for Uveitic Glaucoma

Uveitic glaucoma (UG) is a complex secondary glaucoma caused by intraocular inflammation that disrupts aqueous humor drainage, leading to increased intraocular pressure (IOP) and potential vision loss. While medical therapy is the first-line treatment, glaucoma drainage implants (GDIs) become essential when pharmacologic management fails.
Gianluca Besozzi, Michele Santoro, Flavio Cassano, Milena L’Abbate, Maria Carmela Costa   +4 more
openaire   +1 more source

Silicone Oil–induced Secondary Glaucoma

Okulistyka
Secondary glaucoma induced by silicone oil is one of the most serious complications following vitrectomy with endotamponade. The pathogenesis of elevated intraocular pressure is multifactorial and includes both early mechanisms – such as pupillary block ...
Michał Jabłoński, Mateusz Winiarczyk, Jerzy Mackiewicz   +2 more
doaj   +1 more source