Results 101 to 110 of about 922,810 (288)

Advancing Artificial Intelligence in Myopia Management: From Predicting Progression to Supporting Clinical Decisions

Med Research, EarlyView.
The AI‐enabled multimodal framework for whole‐life myopia management. Graphical abstract illustrates the transition of myopia care from premyopia to myopia, high myopia, and pathologic myopia. Multimodal data, including demographic and refractive information, genetic, behavioral and environmental factors, ophthalmic imaging, and omics profiles, can be ...
Zewei Zhang, Yun Wang, Lifei Zhang, Dongmei Chen, Weijie Zhang, Fang Li, Jibo Zhou   +6 more
wiley   +1 more source

Beyond intraocular pressure: introducing a novel glaucoma-specific PROM for evaluating outcomes after IStent inject implantation combined with phacoemulsification cataract surgery

Scientific Reports
This study aimed to develop and validate a glaucoma-specific patient-reported-outcome-measure (PROM) questionary to assess disease-specific burden across all severities of open-angle glaucoma (OAG), including patients undergoing combined IStent inject ...
José María Martínez-de-la-Casa, María Parrilla-Vallejo, Laura Rodríguez-Aguilar, Virginia Rodríguez-González, Thomas Jacobs, Joaquín María Carratalá-Beltrán   +5 more
doaj   +1 more source

Parkinson's Disease and Retinal Age Gap: A Cross‐Sectional Analysis

Movement Disorders, EarlyView.
Abstract Background Deep‐learning models are capable of predicting age from retinal scans and the difference between this and chronological age, retinal age gap, has been shown to be significantly associated with risk of mortality, cardiovascular diseases, and kidney failure.
Akshay Narayan, Oscar Earle, Yukun Zhou, Axel Petzold, Rimona S. Weil, Alastair K. Denniston, Anthony P. Khawaja, Pearse A. Keane, Zhuoting Zhu, Siegfried K. Wagner   +9 more
wiley   +1 more source

Utility values for glaucoma patients in Korea.

PLoS ONE, 2018
ObjectivesAlthough determining the quality of life among glaucoma patients has important clinical and public health implications, the utility value of glaucoma patients has not yet been determined in Korea.MethodsThe Korean National Health and Nutrition ...
Seulggie Choi, Jin A Choi, Jin Woo Kwon, Sang Min Park, Donghyun Jee   +4 more
doaj   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Severe open angle glaucoma in hereditary hemorrhagic telangiectasia

Clinical Case Reports, 2015
Key clinical messageHereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease. Conjunctival telangiectasias and retinal vascular malformations are known ocular manifestations. We report here the first case of open angle glaucoma in a patient with HHT caused by a nonsense mutation, C471X in the ACVRL1 gene.
Kuchtey, Rachel W, Naratadam, George T, Kuchtey, John   +2 more
openaire   +2 more sources

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

A retrospective study of the association between Fuchs’ endothelial dystrophy and glaucoma

Clinical Ophthalmology, 2014
Greg D Rice,1 Kristin Wright,1 Steven M Silverstein2 1Kansas City University of Medicine and Biosciences, Kansas City, MO, USA; 2Silverstein Eye Centers, Kansas City, MO, USA Objective: The goal of this study was to examine a possible clinical ...
Rice GD, Wright K, Silverstein SM
doaj  

Economic evaluation of screening for open angle glaucoma [PDF]

, 2008
Objectives: The aim of this study was to assess the cost-effectiveness of screening for open-angle glaucoma (OAG) in the United Kingdom, given that OAG is an important cause of blindness worldwide.
Burr, Jennifer M., Hernandez, Rodolfo A., Vale, Luke D., Hernández, Rodolfo Andrés, Burr, Jennifer Margaret, Vale, Luke David, OAG Screening Project Group, Burr, Jennifer M.; id_orcid   +7 more
core   +1 more source

starU‐Net: An enhanced U‐Net architecture with star operation and multi‐view fusion for improved vessel segmentation

VIEW, EarlyView.
Low‐contrast capillaries are often missed or fragmented by segmentation models, so we developed a shallow four‐level starU‐Net that combines star operation‐based feature extraction with dynamic snake convolution‐based multi‐view fusion for improved thin vessel continuity.
Mengwei Bai, Li Tong, Jing Lin, Peng Huang   +3 more
wiley   +1 more source