Results 81 to 90 of about 35,176 (249)
Spatial multi‐omics of the mouse ocular globe after retinal ischemia‐reperfusion (RIR) injury identifies the ganglion cell layer (GCL) as an immunometabolic niche where Trem2+ microglia closely associate with stressed retinal ganglion cells (RGCs) through Trem2‐Apoe signaling.
Yunhong Shi +12 more
wiley +1 more source
A retrospective study of the association between Fuchs’ endothelial dystrophy and glaucoma
Greg D Rice,1 Kristin Wright,1 Steven M Silverstein2 1Kansas City University of Medicine and Biosciences, Kansas City, MO, USA; 2Silverstein Eye Centers, Kansas City, MO, USA Objective: The goal of this study was to examine a possible clinical ...
Rice GD, Wright K, Silverstein SM
doaj
The regulation of stem cell fate and its application in neural regeneration
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He +3 more
wiley +1 more source
Objectives: To determine patterns of peripapillary retinal nerve fiber layer (RNFL) damage in early- and late-stage glaucoma based on the Disc Damage Likelihood Scale (DDLS).
Noor UlAin +2 more
doaj +1 more source
Optic Nerve Thickness Assessed by Ocular Ultrasonography in Obstructive Sleep Apnea
Objectives Obstructive sleep apnea (OSA) has been associated with various ocular complications, yet ultrasonographic evaluation of optic nerve thickness and its relationship with nocturnal hypoxemia remains poorly understood. This study aimed to evaluate optic nerve thickness and globe dimensions using ocular ultrasonography in patients with different ...
Buğra Kerget +4 more
wiley +1 more source
Correlation of Average RNFL Thickness Using the STRATUS OCT with the Perimetric Staging of Glaucoma
Objective: To determine the correlation between average peripapillary retinal nerve fiber layer (RNFL) thickness measured with time domain optical coherence tomography (TD-OCT) in normal and glaucoma eyes. Methods: This was a cross-sectional study of
Sharah Mae G. Kaw, MD +3 more
doaj
ABSTRACT Background Scleromyxedema (SMX) is a cutaneous mucinosis characterised by an abnormal accumulation of mucin in the skin and limited treatment options. Assessment of therapy response during treatment is challenging. Objectives Patients with SMX receiving high‐dose intravenous IVIg therapy were included to assess validity of the double modified ...
Julia K. Winkler, Alexander H. Enk
wiley +1 more source
Prone Positioning–Associated Anisocoria: A Diagnostic Pitfall in Critical Care
Eye &ENT Research, EarlyView.
Saim Mahmood Khan +5 more
wiley +1 more source
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu +4 more
wiley +1 more source
Mapping Causal Biology: Mendelian Randomization in the Era of Big Data
Mendelian randomization (MR) leverages genetic variants to mitigate confounding biases in causal inference. This review systematically maps MR's methodological evolution, highlights its expanding applications in epidemiology and drug target validation, and outlines future directions for overcoming current biases through dynamic, multi‐omics, and cross ...
Xuanlu Shen +10 more
wiley +1 more source

