Results 61 to 70 of about 57,809 (287)

Effect of idiopathic epiretinal membrane on macular ganglion cell complex measurement in eyes with glaucoma

Frontiers in Medicine, 2022
Background/objectivesCo-existing idiopathic epiretinal membrane (ERM) and glaucoma complicate the estimation of glaucoma severity via optical coherence tomography (OCT).
Shunsuke Nakakura, Ryo Asaoka, Ryo Asaoka, Ryo Asaoka, Ryo Asaoka, Satomi Oogi, Ryota Aoki, Etsuko Terao, Kanae Ueda, Yoshiaki Kiuchi   +9 more
doaj   +1 more source

Comparison of Outcomes between Endoscopic and Transcleral Cyclophotocoagulation. [PDF]

, 2017
Importance: Traditionally cyclophotocoagulation has been reserved as a treatment of last resort for eyes with advanced stage glaucoma, but increasingly it is offered to eyes with less severe disease.
Beardsley, Robert, Caprioli, Joseph, Coleman, Anne L, Giaconi, JoAnn A, Hubschman, Jean-Pierre, Law, Simon K, Nouri-Mahdavi, Kouros, Schwartz, Steven D   +7 more
core   +3 more sources

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

Advanced Science, EarlyView.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao, Xiaoyu Li, Hongwei Wang, Zongyi Li, Qun Wang, Yangyang Zhang, Xu Jing, Xia Qi, Qingjun Zhou, Shengqian Dou, Lixin Xie   +10 more
wiley   +1 more source

Optic disc vessel density in nonglaucomatous and glaucomatous eyes: an enhanced-depth imaging optical coherence tomography angiography study

Clinical Ophthalmology, 2018
Yuji Yoshikawa,1 Takuhei Shoji,1 Junji Kanno,1 Itaru Kimura,1 Masanori Hangai,2 Kei Shinoda1 1Department of Ophthalmology, Saitama Medical University, Saitama, Japan; 2Hangai Eye Institute, Saitama, Japan Purpose: To evaluate the ability of enhanced ...
Yoshikawa Y, Shoji T, Kanno J, Kimura I, Hangai M, Shinoda K   +5 more
doaj  

Central corneal thickness in primary angle closure and open angle glaucoma

Journal of Ophthalmic & Vision Research, 2014
Purpose: To quantitatively analyze central corneal thickness (CCT) in patients with primary angle closure glaucoma (PACG) and primary open-angle glaucoma (POAG), and to evaluate its correlation with severity of glaucoma.
Sasan Moghimi, Hamidreza Torabi, Hesam Hashemian, Heydar Amini, Shan Lin   +4 more
doaj   +1 more source

Ocular surface disease in glaucoma patients on topical medications and its relation to duration of treatment and number of medications

Journal of Clinical Ophthalmology and Research, 2022
Background: Topical antiglaucoma medications can alter the tear film and lead to ocular surface disease (OSD). Aim: This study was done to check for the presence of OSD in patients of glaucoma on topical antiglaucoma medications and to analyze the ...
Samruddhi N Chanekar, Ugam P S. Usgaonkar, Shekhar O Akarkar   +2 more
doaj   +1 more source

Lamina Cribrosa and Choroid Features and Their Relationship to Stage of Pseudoexfoliation Glaucoma. [PDF]

, 2018
PurposeTo better understand the relationship of lamina cribrosa (LC) and choroid features to the severity of pseudoexfoliation glaucoma (PXG).MethodsIn this cross-sectional study, 137 eyes of 122 subjects (47 eyes with moderate/advanced PXG [mean ...
Chen, Rebecca, Fard, Masoud Aghsaei, Moghimi, Sasan, Mohammadi, Massood, Motamed-Gorji, Nazgol, Nekoozadeh, Shahbaz, Weinreb, Robert N   +6 more
core  

Severe Hypotony After Glaucoma Filtering Surgery

, 2019
Purpose: To develop surgical tactic based on the results of treating severe hypotony after anti-glaucoma surgery. Patients and methods: A retrospective analysis of 28 eyes of 27 patients (11 females, 16 males) was held. Mean age of patients was 13 to 85 years (55±2). All the patients had severe[for full text, please go to the a.m. URL]
Ivanova, E, Ivanova, D
openaire   +2 more sources

High‐Resolution Genomic Characterization of WAGR Spectrum Disorder: Insights From a Novel Cohort and Literature Synthesis, and Validation of Patient‐Reported Data

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT WAGR spectrum disorder (WAGRSD) is an ultra‐rare congenital disorder caused by heterozygous deletion of chromosome 11p13. While classically associated with Wilms tumor, Aniridia, Genitourinary anomalies, and a Range of developmental delays, accurate delineation of the deletion is critical for prognosis because the phenotypic spectrum extends ...
Andrew M. George, Bamelak T. Duki, Zoe S. Katz, Aravind Viswanathan, Suzanne P. MacFarland, Evan R. Hathaway, Caitlin Monahan, John Morris, Kelly L. Trout, Shari M. Krantz, Arupa Ganguly, Jennifer M. Kalish   +11 more
wiley   +1 more source