An RNA Sequencing Analysis of Glaucoma Genesis in Mice [PDF]
Glaucoma is the leading cause of irreversible blindness in people over the age of 60, accounting for 6.6 to 8% of all blindness in 2010, but there is still much to be learned about the genetic origins of the eye disease. With the modern development of Next-Generation Sequencing (NGS) technologies, scientists are starting to learn more about the genetic
arxiv
GAMMA Challenge:Glaucoma grAding from Multi-Modality imAges [PDF]
Color fundus photography and Optical Coherence Tomography (OCT) are the two most cost-effective tools for glaucoma screening. Both two modalities of images have prominent biomarkers to indicate glaucoma suspected. Clinically, it is often recommended to take both of the screenings for a more accurate and reliable diagnosis.
arxiv
Geometric Deep Learning to Identify the Critical 3D Structural Features of the Optic Nerve Head for Glaucoma Diagnosis [PDF]
Purpose: The optic nerve head (ONH) undergoes complex and deep 3D morphological changes during the development and progression of glaucoma. Optical coherence tomography (OCT) is the current gold standard to visualize and quantify these changes, however the resulting 3D deep-tissue information has not yet been fully exploited for the diagnosis and ...
arxiv
Topical prostaglandin analogues and conjunctival inflammation in uveitic glaucoma. [PDF]
A pilot study to determine whether topical prostaglandin analogues alter the expression of conjunctival inflammatory markers in patients with uveitic glaucoma.Prospective, single-masked case series of 20 patients with uveitis and secondary raised ...
Gurbaxani, A+3 more
core +1 more source
Abstract Aim Analysis of age at time of detection and surgery of dense unilateral cataract and investigation of best‐corrected visual acuity (BCVA) in a nationwide register‐based cohort study, based on the routine of maternity ward eye screening. Methods Data were derived from the Paediatric Cataract Register (PECARE).
David Wackerberg+8 more
wiley +1 more source
Efficacy of Ahmed Glaucoma Valve and Trabeculectomy With Mitomycin-C in Pediatric Glaucoma
Objective: To compare the efficacy between Ahmed glaucoma valve surgery and Trabeculectomy with Mitomycin-c in pediatric glaucoma. Study design and setting: Quasi-experimental study was conducted at Pediatric Ophthalmology Department, ISRA Post graduate
Manzoor Ahmed Khan+5 more
doaj +1 more source
The 3D Structural Phenotype of the Glaucomatous Optic Nerve Head and its Relationship with The Severity of Visual Field Damage [PDF]
$\bf{Purpose}$: To describe the 3D structural changes in both connective and neural tissues of the optic nerve head (ONH) that occur concurrently at different stages of glaucoma using traditional and AI-driven approaches. $\bf{Methods}$: We included 213 normal, 204 mild glaucoma (mean deviation [MD] $\ge$ -6.00 dB), 118 moderate glaucoma (MD of -6.01
arxiv
Wearable sensors, empowered by AI and smart materials, revolutionize healthcare by enabling intelligent disease diagnosis, personalized therapy, and seamless health monitoring without disrupting daily life. This review explores cutting‐edge advancements in smart materials and AI‐driven technologies that empower wearable sensors for diagnostics and ...
Shuwen Chen+14 more
wiley +1 more source
Medicines legislation and regulation in the United Kingdom 1500‐2020
The initial purposes of regulation of medicines in England, and latterly in the United Kingdom, were principally to raise government revenue, to discourage murder by poisoning and to regulate the activities of pharmacists. It was only much later that regulators sought to ensure that medicines were of good quality, reasonably safe, and at least somewhat
Robin E. Ferner, Jeffrey K. Aronson
wiley +1 more source
Circumpapillary OCT-Focused Hybrid Learning for Glaucoma Grading Using Tailored Prototypical Neural Networks [PDF]
Glaucoma is one of the leading causes of blindness worldwide and Optical Coherence Tomography (OCT) is the quintessential imaging technique for its detection. Unlike most of the state-of-the-art studies focused on glaucoma detection, in this paper, we propose, for the first time, a novel framework for glaucoma grading using raw circumpapillary B-scans.
arxiv