Results 51 to 60 of about 102,870 (301)

Non‐RASopathy Genetic Syndromes Identified as the Molecular Cause of Disease in Patients Previously Diagnosed With Noonan Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Noonan Syndrome (NS) is a clinically and genetically heterogeneous condition characterized by typical facial dysmorphisms, short stature, congenital heart defects, and developmental delays. While variants in genes such as PTPN11, SOS1, and RAF1 account for most genetically confirmed cases, diagnosis is challenging due to phenotypic overlap ...
Gabriela Jeesoo Kim, Alexsandra Christianne Malaquias, Debora Romeo Bertola, Raissa Carneiro Rezende, Laurana De Polli Cellin, Lucas Vieira Lacerda Pires, Ana Maria Santillan‐Vasconez, Antônio Marcondes Lerario, Renata da Cunha Scalco, Alexander Augusto de Lima Jorge   +9 more
wiley   +1 more source

Three-Dimensional Spectral-Domain Optical Coherence Tomography Data Analysis for Glaucoma Detection [PDF]

, 2013
Purpose: To develop a new three-dimensional (3D) spectral-domain optical coherence tomography (SD-OCT) data analysis method using a machine learning technique based on variable-size super pixel segmentation that efficiently utilizes full 3D dataset to ...
C Ajtony, CK Leung, ER DeLong, Gadi Wollstein, H Ishikawa, Hiroshi Ishikawa, J Friedman, J Xu, J Xu, JA Hanley, JB Shi, Joel S. Schuman, JS Schuman, Juan Xu, KA Townsend, Larry Kagemann, Lindsey S. Folio, LS Folio, ME Pons, ML Gabriele, ML Gabriele, MR Hee, MR Hee, Pedro Gonzalez, Richard A. Bilonick, W Drexler, Zach Nadler   +26 more
core   +3 more sources

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, EarlyView.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Cost–benefit analysis of screening programme for diabetic retinopathy in Bulgaria

British Journal of Clinical Pharmacology, EarlyView.
Aims Late‐diagnosed diabetic retinopathy (DR) is difficult and expensive to treat. Screening programmes can identify the disease early and reduce the costs of its future treatment. This study aims to analyse the cost–benefit of screening programmes for DR.
Iva Nenkova, Yoana Lilova, Alexander Oscar, Alina Levi, Maria Kamusheva, Guenka Petrova   +5 more
wiley   +1 more source

Improving Visual Field Examination of the Macula Using Structural Information [PDF]

, 2018
Purpose: To investigate a novel approach for structure-function modeling in glaucoma to improve visual field testing in the macula. Methods: We acquired data from the macular region in 20 healthy eyes and 31 with central glaucomatous damage.
Allegrini, D., Crabb, D. P., Montesano, G., Romano, M. R., Rossetti, L. M.   +4 more
core   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Triggerfish Recording of IOP Patterns in Combined HFDS Minimally Invasive Glaucoma and Cataract Surgery: A Prospective Study [PDF]

, 2021
Bojan Pajic, Mirko Resan, Brigitte Pajic-Eggspuehler, Horace Massa, Željka Cvejić   +4 more
openalex   +1 more source

Driving Innovation: The Impact of National Health Policies on Optometry Research in East Asia

The International Journal of Health Planning and Management, EarlyView.
ABSTRACT This study examines the optometric research landscape in three East Asian countries—China, Japan, and Korea—analysing how research trends align with each country's national health strategies. By evaluating published articles and reviews from national journals between 2006 March 2025, we identify key areas of focus, including paediatric ...
Jihye Ahn, Moonsung Choi
wiley   +1 more source

Glaucoma drainage device implantation and cyclophotocoagulation in the management of refractory glaucoma after Descemet-stripping automated endothelial keratoplasty [PDF]

International Journal of Ophthalmology
AIM: To compare the surgical outcomes of glaucoma drainage device implantation (GDI) and trans-scleral neodymium:YAG cyclophotocoagulation (CPC) in the management of refractory glaucoma after Descemet-stripping automated endothelial keratoplasty (DSAEK).
Min-Shu Wang, Xue-Chuan Dong, Mi-Yun Zheng, Xiang Fan, Ge-Ge Xiao, Jing Hong, Ling-Ling Wu   +6 more
doaj   +1 more source

Fluorescence Lifetime Imaging Techniques—A Review on Principles, Applications and Clinical Relevance

Journal of Biophotonics, EarlyView.
This article gives an overview of the most frequently used fluorescence‐lifetime imaging (FLIM) techniques, their capabilities and typical applications in biology and clinical studies. ABSTRACT This article gives an overview of the most frequently used fluorescence‐lifetime imaging (FLIM) techniques, their capabilities, and typical applications ...
V. I. Shcheslavskiy, M. V. Shirmanova, K. S. Yashin, A. C. Rück, M. C. Skala, W. Becker   +5 more
wiley   +1 more source