Results 71 to 80 of about 3,633,295 (206)

Microbial metabolite indole‐3‐propionic acid preserves astrocytic mitochondrial mitofusin 2 to limit neuroinflammation after traumatic brain injury

Interdisciplinary Medicine, EarlyView.
Following traumatic brain injury, indole‐3‐propionic acid (IPA) directly targets the aryl hydrocarbon receptor on astrocytes in the peri‐lesional cortex; this suppresses interferon regulatory factor 1‐driven transcription of the E3 ubiquitin ligase RFFL (ring finger and FYVE‐like domain containing E3 ubiquitin protein ligase).
Ziwen Zhang, Kai Wang, Liangbo Wang, Wencong Li, Hao Guo, Meng Xu, Tinghao Wang, Jiahui Ren, Ting Zhu, Jiahui Wang, Wenxing Cui, Jinpeng Zhou, Yang Tian, Liying Han, Chengxuan Guo, Shuoyao Ma, Qiang Wang, Zhihong Li, Yaning Cai, Jingyu Dong, Xun Wu, Haixiao Liu, Yan Qu   +22 more
wiley   +1 more source

PROFIL KADAR GLIAL FIBRILLARY ACIDIC PROTEIN (GFAP) SERUM PADA PASIEN CEDERA OTAK BERAT [PDF]

, 2016
Pendahuluan. Glial fibrillary acidic protein merupakan protein yang sangat spesifik untuk otak (highly brain specific protein) yang tidak dihasilkan sel lain di luar sistem saraf pusat, dan petanda yang sangat spesifik untuk otak.
ARIEF SUKMA HARIYANTO, NIM011318156308
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Glial Fibrillary Acidic Protein as a Potential Indicator for Symptomatic Intracranial Hemorrhage in Acute Ischemic Patients Undergoing Endovascular Thrombectomy

Minghao Li,1,2,* Hua Liu,1,3,* Mingyang Xu,1,3 Baiyang Yu,3,4 Minwang Guo,1,3 Xiaorong Wang,1,3 Guomei Shi,1,3 Rujuan Zhou1,3 1Stroke Center, Taixing People’s Hospital, Taixing, Jiangsu, People’s Republic of China; 2Department of Vascular Surgery,
Liu H, Guo M, Xu M, Yu B, Zhou R, Shi G, Wang X, Li M   +7 more
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Harnessing Aggregation‐Induced Emission for Advanced Disease Diagnosis: Mechanisms, Strategies and Future Perspectives

Medicine Bulletin, EarlyView.
The figure was created in BioRender.com. ABSTRACT Accurate and early diagnosis remains a key challenge in modern disease management. Conventional diagnostic methods often suffer from limitations in sensitivity, spatial resolution, and practical usability.
Zizhuo Du, Li Song, Xingrui Chen, Jun Jing, Yingchen Wang, Yue Jiang, Jiahui Gao, Dan Li, Feiran Xie, Peihong Xiao, Ben Zhong Tang   +10 more
wiley   +1 more source

3082 Glial fibrillary acidic protein astrocytopathy (GFAP-A): two Australian cases highlight the clinical heterogeneity

3082 Glial fibrillary acidic protein astrocytopathy (GFAP-A): two Australian cases highlight the clinical ...
Mustafa Al-Musawi (20210703), Alex A Chen (20210709), Matthew Shrimpton (13086123), Abhishek A Malhotra (20210706)   +3 more
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High‐Fat Diet Exacerbates Neuropathology in a Transgenic Mouse Model of Multiple System Atrophy

Movement Disorders, EarlyView.
Abstract Background Multiple system atrophy (MSA) is a rare and devastating neurodegenerative disorder. Accumulating clinical and preclinical evidence suggests that diabetes and insulin resistance may adversely influence MSA pathophysiology. Objective We investigated the potential association between diabetes, impaired glucose homeostasis, and MSA ...
Marie‐Laure Arotcarena, Anna Delamarre, Miguel Lopez‐Cuina, Hugo Martin, Elio Balpe, Xavier Fioramonti, Erwan Bezard, Wassilios G. Meissner   +7 more
wiley   +1 more source

Cardiopulmonary-Bypass Glial Fibrillary Acidic Protein Correlates With Neurocognitive Skills

, 2018
Neuro-cognitive deficits at school starting age may affect as many as 50% of children who underwent cardiac surgery for complex congenital heart diseases (CHD).
Falasco, Gianclaudio, Suppiej, Agnese, Vedovelli, Luca, Simonato, Manuela, Manuela Simonato, Padalino, Massimo, Cogo, Paola, Virgilio P. Carnielli, Giovanni Stellin, Gianclaudio Falasco, Paola Cogo, Stellin, Giovanni, Luca Vedovelli, Massimo Padalino, Carnielli, Virgilio P., Stefano Sartori, Sartori, Stefano, Carnielli, Virgilio P, Agnese Suppiej   +18 more
core   +1 more source

COVID‐19 Amplifies Sex‐Specific Dopamine and Glial Responses in a Parkinson's Disease Mouse Model

Movement Disorders, EarlyView.
Abstract Background Exposure to environmental agents, including viral infections, may increase Parkinson's disease (PD) susceptibility, especially in males, but the neurodegenerative risk extent of COVID‐19 remains uncertain. Objectives We investigated the plausible link between severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and
Ifeoluwa Awogbindin, Mélanie Bourque, Marc Morissette, Marie‐Ève Hamelin, Chantal Rhéaume, Jared VanderZwaag, Antonia Landwehr, Disha Patel, Guy Boivin, Marie‐Ève Tremblay, Thérèse Di Paolo   +10 more
wiley   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Estudo dos derivados da guanina como agentes protetores e tróficos em astrócitos e neurônios cerebelares [PDF]

, 2004
Dissertação (mestrado) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Programa de Pós-Graduação em Neurociências.Os nucleotídeos e o nucleosídeo derivados da guanina (DG) têm sido implicados em diversas funções extracelulares ...
Francisco, Sheila Regina Schmidt
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