Results 191 to 200 of about 16,058 (248)

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

MotAB-like machinery drives the movement of MreB filaments during bacterial gliding motility. [PDF]

open access: yesProc Natl Acad Sci U S A, 2018
Fu G   +7 more
europepmc   +1 more source

A Comparison of Classical Constitutive Models for High‐Entropy Alloy Behavior: Effects of Medium Strain Rates and Temperature on Plastic Flow

open access: yesMaterials Genome Engineering Advances, EarlyView.
Four constitutive models are evaluated for FeCoNiCr and Al0.6FeCoNiCr HEAs under wide temperature and strain‐rate conditions. The predictive capabilities and limitations of each model are then critically assessed, with particular emphasis on strain rate sensitivity, temperature dependence, and physically unrealistic responses at extreme loading ...
Yooseob Song   +3 more
wiley   +1 more source

Mathematical Analysis and Simulations of a Cancer Model With Interleukins and Delayed Immunotherapy

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT A new system of delayed differential equations for tumor‐immune system interactions is proposed and studied. The system describes the interactions between tumor cells and the immune system at the most aggressive phase of cancer, where tumor cells have developed mechanisms from earlier stages to evade immune responses.
Laid Boudjellal   +2 more
wiley   +1 more source

On‐Time Meal Delivery Assisted by Drone Resupply

open access: yesNaval Research Logistics (NRL), EarlyView.
ABSTRACT Ensuring timely delivery is crucial with the increasing competition in online meal delivery services. This requires the industry to adopt new technologies and the corresponding operational models, including the use of drones. Concerning the desired features of meal delivery, such as safety and reliability, we propose an operational model that ...
Wenqian Liu, Lindong Liu, Xiangtong Qi
wiley   +1 more source

Drivers of individual plant species contributions to β‐diversity are scale‐dependent

open access: yesOikos, EarlyView.
Species introductions and local extinctions of native species are driving biotic homogenisation in plant communities by reducing β‐diversity. Individual species vary in their contributions to β‐diversity (species contribution to β‐diversity; species‐β), yet our understanding of how species characteristics shape these contributions remains limited ...
Rona Learmonth   +16 more
wiley   +1 more source

Continental accumulation of fads2 copy numbers allows sticklebacks to thrive across a diversity of nutritional landscapes

open access: yesOikos, EarlyView.
Nutrients, including vital organic compounds, vary in availability across ecosystems, with the potential to act as a source of selection for traits that increase nutrient acquisition and biosynthesis. Compared to freshwaters, marine ecosystems are richer in the omega‐3 long‐chain polyunsaturated fatty acid (n‐3 LC‐PUFA) docosahexaenoic acid (DHA ...
Cornelia W. Twining   +12 more
wiley   +1 more source

Evidence for dispersal personality in the guppy across ecological conditions, with a minor effect of relative brain size

open access: yesOikos, EarlyView.
Individuals that disperse typically exhibit specific phenotypical traits that facilitate dispersal and settlement success, known as ‘dispersal syndromes'. Consequentially, characterizing dispersers is crucial to understand other processes such as metapopulation dynamics and biological invasions.
Gilles De Meester   +6 more
wiley   +1 more source

Digital surveillance of animals and nature recovery

open access: yesPeople and Nature, EarlyView.
Abstract Digital surveillance technologies (DSTs) are widely applied in nature recovery for their potential to generate novel data on species and ecosystems through digital tracking, automation (e.g. from hazardous locations) and from newly recruited citizen scientists.
William M. Adams
wiley   +1 more source

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