Glimepiride Administered in Chow Reversibly Impairs Glucose Tolerance in Mice [PDF]
Sulfonylureas are a class of antidiabetes medications prescribed to millions of individuals worldwide. Rodents have been used extensively to study sulfonylureas in the laboratory.
Dana M. Niedowicz +2 more
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Optimization of therapy of type 2 diabetes mellitus with the oral hypoglycemic agent glimepiride [PDF]
Type 2 diabetes is believed to develop as a result of lowered insulin secretion and insulin resistance leading to hyperglycemia. Sulfonylureas stimulateinsulin secretion and thereby decrease blood glucose level which accounts for their wide application ...
Tatiana Ivanovna Romantsova +1 more
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The Many Faces of Glimepiride: on the Question of Interchangeability of Oral Hypoglycemic Agents
The article presents a literature review on the use of glimepiride while treating patients with diabetes mellitus. Characteristics of generic drugs of glimepiride are provided.
N.V. Bezdetko
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Choon Ok Kim,1 Eun Sil Oh,2 Hohyun Kim,3 Min Soo Park1,4 1Department of Clinical Pharmacology, Severance Hospital, Yonsei University College of Medicine, Seoul, 2Department of Pharmaceutical Medicine and Regulatory Sciences, College of Medicine and ...
Kim CO, Oh ES, Kim H, Park MS
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Analisis Cost-Effectiveness Kombinasi Glimepiride-Metformin Dengan Glimepiride-Pioglitazone pada Pasien Diabetes Mellitus Tipe 2 Rawat Jalan [PDF]
Kombinasi glimepiride-metformin merupakan lini pertama pengobatan diabetes mellitus tipe 2 (DMT 2) dan kombinasi glimepiride-pioglitazon saat ini masuk dalam daftar pedoman pelayanan kefarmasian pada pasien diabetes mellitus.
Rahem, Abdul +2 more
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Introduction Nonalcoholic fatty liver disease (NAFLD) with type 2 diabetes mellitus (T2DM) is associated with severe clinical outcomes. MicroRNA (miR)-210 has been reported to be related to T2DM and lipid metabolism. This study aimed to determine whether
Jie Shen +7 more
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Stressed experimental diabetic rats challenged with glimepiride [PDF]
Background: This study was accomplished to evaluate the anticipated effects of glimepiride on some of the hematological parameters and antioxidant enzymes in alloxan-induced diabetic and healthy rats.Methods: In this study, thirty-two adult albino male ...
Hashim, Wissam Sajid +3 more
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Stimulation of glucose utilization in 3T3 adipocytes and rat diaphragm in vitro by the sulphonylureas, glimepiride and glibenclamide, is correlated with modulations of the cAMP regulatory cascade [PDF]
The long-term hypoglycemic activity of sulphonylurea drugs has been attributed, in part at least, to the stimulation of glucose utilization in extra-pancreatic tissues. The novel sulphonylurea, glimepiride, gives rise to a longer lasting reduction in the
Wetekam, Eva-Marlen +5 more
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Dissolution of Glimepiride–Captisol Inclusion Complexes [PDF]
This present study investigated the effect of Captisol, a chemically modified cyclodextrin, on the in vitro dissolution of glimepiride. We prepared glimepiride–Captisol complexes of different mass ratios (1:1, 1:2, and 1:3 w/w) by a physical mixing or ...
Christian Agatemor +16 more
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The effect of piperine on the pharmacokinetics and pharmacodynamics of glimepiride in normal as well as diabetic rats was studied. In normal and streptozotocin induced diabetic rats the combination of glimepiride with piperine increased all the ...
Ciddi Veeresham +2 more
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