Results 11 to 20 of about 2,551 (122)

Glimepiride Administered in Chow Reversibly Impairs Glucose Tolerance in Mice [PDF]

open access: yesJournal of Diabetes Research, 2018
Sulfonylureas are a class of antidiabetes medications prescribed to millions of individuals worldwide. Rodents have been used extensively to study sulfonylureas in the laboratory.
Dana M. Niedowicz   +2 more
doaj   +2 more sources

Optimization of therapy of type 2 diabetes mellitus with the oral hypoglycemic agent glimepiride [PDF]

open access: yesСахарный диабет, 2010
Type 2 diabetes is believed to develop as a result of lowered insulin secretion and insulin resistance leading to hyperglycemia. Sulfonylureas stimulateinsulin secretion and thereby decrease blood glucose level which accounts for their wide application ...
Tatiana Ivanovna Romantsova   +1 more
doaj   +2 more sources

The Many Faces of Glimepiride: on the Question of Interchangeability of Oral Hypoglycemic Agents

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2014
The article presents a literature review on the use of glimepiride while treating patients with diabetes mellitus. Characteristics of generic drugs of glimepiride are provided.
N.V. Bezdetko
doaj   +2 more sources

Pharmacokinetic interactions between glimepiride and rosuvastatin in healthy Korean subjects: does the SLCO1B1 or CYP2C9 genetic polymorphism affect these drug interactions?

open access: yesDrug Design, Development and Therapy, 2017
Choon Ok Kim,1 Eun Sil Oh,2 Hohyun Kim,3 Min Soo Park1,4 1Department of Clinical Pharmacology, Severance Hospital, Yonsei University College of Medicine, Seoul, 2Department of Pharmaceutical Medicine and Regulatory Sciences, College of Medicine and ...
Kim CO, Oh ES, Kim H, Park MS
doaj   +1 more source

Analisis Cost-Effectiveness Kombinasi Glimepiride-Metformin Dengan Glimepiride-Pioglitazone pada Pasien Diabetes Mellitus Tipe 2 Rawat Jalan [PDF]

open access: yes, 2023
Kombinasi glimepiride-metformin merupakan lini pertama pengobatan diabetes mellitus tipe 2 (DMT 2) dan kombinasi glimepiride-pioglitazon saat ini masuk dalam daftar pedoman pelayanan kefarmasian pada pasien diabetes mellitus.
Rahem, Abdul   +2 more
core   +5 more sources

Comparison of glimepiride and linagliptin in the treatment of non-alcoholic hepatic disease with type 2 diabetes mellitus

open access: yes, 2023
Introduction Nonalcoholic fatty liver disease (NAFLD) with type 2 diabetes mellitus (T2DM) is associated with severe clinical outcomes. MicroRNA (miR)-210 has been reported to be related to T2DM and lipid metabolism. This study aimed to determine whether
Jie Shen   +7 more
core   +1 more source

Stressed experimental diabetic rats challenged with glimepiride [PDF]

open access: yes, 2023
Background: This study was accomplished to evaluate the anticipated effects of glimepiride on some of the hematological parameters and antioxidant enzymes in alloxan-induced diabetic and healthy rats.Methods: In this study, thirty-two adult albino male ...
Hashim, Wissam Sajid   +3 more
core   +1 more source

Stimulation of glucose utilization in 3T3 adipocytes and rat diaphragm in vitro by the sulphonylureas, glimepiride and glibenclamide, is correlated with modulations of the cAMP regulatory cascade [PDF]

open access: yes, 1994
The long-term hypoglycemic activity of sulphonylurea drugs has been attributed, in part at least, to the stimulation of glucose utilization in extra-pancreatic tissues. The novel sulphonylurea, glimepiride, gives rise to a longer lasting reduction in the
Wetekam, Eva-Marlen   +5 more
core   +1 more source

Dissolution of Glimepiride–Captisol Inclusion Complexes [PDF]

open access: yes, 2020
This present study investigated the effect of Captisol, a chemically modified cyclodextrin, on the in vitro dissolution of glimepiride. We prepared glimepiride–Captisol complexes of different mass ratios (1:1, 1:2, and 1:3 w/w) by a physical mixing or ...
Christian Agatemor   +16 more
core   +1 more source

Effect of Piperine on the Pharmacokinetics and Pharmacodynamics of Glimepiride in Normal and Streptozotocin - Induced Diabetic Rats

open access: yesNatural Product Communications, 2012
The effect of piperine on the pharmacokinetics and pharmacodynamics of glimepiride in normal as well as diabetic rats was studied. In normal and streptozotocin induced diabetic rats the combination of glimepiride with piperine increased all the ...
Ciddi Veeresham   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy