Results 21 to 30 of about 2,551 (122)

Efficacy and safety of dulaglutide monotherapy compared with glimepiride in Chinese patients with type 2 diabetes: Post‐hoc analyses of a randomized, double‐blind, phase III study

Journal of Diabetes Investigation, 2020
Aims/Introduction To investigate the efficacy/safety of dulaglutide once‐weekly monotherapy versus glimepiride in Chinese patients with type 2 diabetes.
Li Xin Shi, Xiao Min Liu, Yong Quan Shi, Quan Min Li, Jian Hua Ma, Yan Bing Li, Li Ying Du, Feng Wang, Lu Lu Chen   +8 more
doaj   +1 more source

Detection and development of a quantitation method for undeclared compounds in antidiabetic biologically active additives and its validation by high performance liquid chromatography [PDF]

Pharmacia, 2022
An isocratic, high-performance liquid chromatography (HPLC) quantitation method was developed for the quantitative determination of metformin, glibenclamide, gliclazide, glimepiride in some antidiabetic biologically active additives.
Virab Gurgen Kirakosyan, Avetis Hovhannes Tsaturyan, Lilit Eduard Poghosyan, Ella Vardan Minasyan, Hayk Razmik Petrosyan, Lusine Yurik Sahakyan, Tatevik Hovhannes Sargsyan   +6 more
doaj   +3 more sources

The solid-state modification for solubility enhancement of practically insoluble glimepiride: A systematic review [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Solubility is a crucial physicochemical property of pharmaceuticals that directly influences the absorption and bioavailability of drugs within the human body.
Fitrianti Darusman, Iyan Sopyan, Nadya Azzahra, Taofik Rusdiana   +3 more
doaj   +1 more source

Comparative study of Dapagliflozin versus Glimepiride effect on insulin regulated aminopeptidase (IRAP) and interleukin-34 (IL-34) in patient with type 2 diabetes mellitus

Scientific Reports, 2023
Type 2 diabetes mellitus (T2DM) is one of the most common diseases, that managed by several medications such as Glimepiride and Dapagliflozin. This study aims to compare the effects of Dapagliflozin versus Glimepiride on glycemic control, insulin ...
Rania Zekry, Gamal A. Omran, Nashwa M. El-Gharbawy, Rehab H. Werida   +3 more
doaj   +1 more source

Glimepiride reduces the expression of PrPc, prevents PrPSc formation and protects against prion mediated neurotoxicity in cell lines. [PDF]

PLoS ONE, 2009
BACKGROUND:A hallmark of the prion diseases is the conversion of the host-encoded cellular prion protein (PrP(C)) into a disease related, alternatively folded isoform (PrP(Sc)). The accumulation of PrP(Sc) within the brain is associated with synapse loss
Clive Bate, Mourad Tayebi, Luisa Diomede, Mario Salmona, Alun Williams   +4 more
doaj   +1 more source

Comparison of Vildagliptin-Metformin and Glimepiride-Metformin Treatments in Type 2 Diabetic Patients [PDF]

Diabetes & Metabolism Journal, 2011
BackgroundThe present study investigated the efficacy and safety of vildagliptin-metformin treatment compared to those of glimepiride-metformin treatment for type 2 diabetes.MethodsIn a randomized, open-label, comparative study, 106 patients with type 2 ...
Hyun Jeong Jeon, Tae Keun Oh
doaj   +1 more source

Efek Pemberian Metformin dan Metformin+Glimepiride terhadap Kadar HbA1c pada Pasien Diabetes Mellitus Tipe 2

Jurnal Manajemen dan Pelayanan Farmasi, 2022
Diabetes is a chronic metabolic disease and management of DM begins with a helthy lifestyle with early administration of antidiabetic drug. Metformin is the first line therapy in the management of DM. Combination therapy is given if blood sugar level and
Fitri Apriliany, Elis Cholisah, Karina Erlianti   +2 more
doaj   +1 more source

Formulation and evaluation of fast disintegrating tablet of glimepiride

Journal of Contemporary Pharmacy, 2018
Glimepiride is the third generation sulphonylurea agent, used for the treatment of type II diabetes mellitus. Glimepiride is given once daily in doses from 1-4 mg.
Arooj Khalid, Roma Qayyum, Minahil Athar, Ujala Younas, Misbah Hameed, Tehseen Sehar, Fatima Amin, Bazgha Gul   +7 more
doaj   +1 more source

Comparative evaluation of safety and efficacy of glimepiride and sitagliptin in combination with metformin in patients with type 2 diabetes mellitus: Indian multicentric randomized trial - START Study

Indian Journal of Endocrinology and Metabolism, 2017
Background and Objective: Modern sulfonylureas like glimepiride offer effective glycemic control with extrapancreatic benefits and good tolerability. The objective of the present study was to evaluate and compare safety and efficacy of glimepiride and ...
T V Devarajan, S Venkataraman, Narayanan Kandasamy, Abraham Oomman, Hari Kishan Boorugu, S. K. P. Karuppiah, Dushyant Balat   +6 more
doaj   +1 more source

Influence of losartan on the hypoglycemic activity of glimepiride in normal and diabetic rats

Therapeutic Advances in Endocrinology and Metabolism, 2013
Background: The influence of losartan on the hypoglycemic effect of glimepiride was studied in normal and diabetic rats. Method: Losartan and glimepiride were studied at a dose of 4.5 and 0.09 mg/kg and in normal and diabetic rats, respectively.
T.E.G.K. Murthy, Manogna K. Kommineni, Candasamy Mayuren   +2 more
doaj   +1 more source