Results 231 to 240 of about 263,515 (247)

One‐Stone‐Two‐Birds Carrier‐Free Nano‐Cocktail Enables Synergistic Eradication of Cancer Cells/Stem Cells in Breast Cancer Treatment

Exploration, EarlyView.
ABSTRACT Cancer stem cells (CSCs) are widely recognized as the culprits of chemoresistance, tumor metastasis, and relapse. Moreover, most chemotherapeutic drugs not only fail to eliminate CSCs effectively, but also induce the acquisition of stemness characteristics in non‐stem cancer cells. Herein, we propose a cancer cells/CSCs double‐killing modality
Tongyao Zhao, Yao Chen, Haimeng Yuan, Shuqian Yang, Hongyuan Zhang, Yuequan Wang, Shenwu Zhang, Qin Chen, Jin Sun, Zhonggui He, Cong Luo   +10 more
wiley   +1 more source

Determinants of poor prognosis after surgery for glioblastoma: A retrospective analysis of predictors of morbidity and mortality in a low-middle income country. [PDF]

Pak J Med Sci
Irshad S, Qadri HM, Sarwar A, Khalid MF, Sajjad O, Jamil M, Tayyab MH, Bashir A.   +7 more
europepmc   +1 more source

Targeting MGAT4A‐Mediated N‐Glycosylation as a Therapeutic Strategy to Inhibit Glioblastoma Stem Cell Invasion

Exploration, EarlyView.
ABSTRACT Glioblastoma (GBM) is the most aggressive type of primary brain tumor, and its invasive properties contribute significantly to incomplete surgical resection and tumor recurrence. Despite extensive clinical efforts to mitigate GBM invasion, targeted therapies against GBM stem cells (GSCs), which drive invasion, remain incompletely understood ...
Rui Niu, Meichen Liu, Qingshan Yang, Jinlong Yin   +3 more
wiley   +1 more source

Causal relationships between blood metabolites and glioblastoma risk: a large-scale Mendelian randomization study. [PDF]

Discov Oncol
Huang L, Tang Y, Tan Y, Lei W, Wang Y, Luo Y.   +5 more
europepmc   +1 more source

The Temozolomide Mutational Signature: Mechanisms, Clinical Implications, and Therapeutic Opportunities in Primary Brain Tumor Management. [PDF]

Cells
Yaacov A, Gillis R, Salim J, Katz D, Asna N, Paldor I, Grinshpun A.   +6 more
europepmc   +1 more source

Identification of SAMD9 as an adaptive response gene to environmental changes and its association with overall survival and immunotherapeutic response in glioblastoma. [PDF]

Cancer Cell Int
Li F, Lei C, Luo M, Bi W, Li Y, Fu S, Yang K.   +6 more
europepmc   +1 more source

Glioblastoma-A Contemporary Overview of Epidemiology, Classification, Pathogenesis, Diagnosis, and Treatment: A Review Article. [PDF]

Int J Mol Sci
Królikowska K, Błaszczak K, Ławicki S, Zajkowska M, Gudowska-Sawczuk M.   +4 more
europepmc   +1 more source