Results 251 to 260 of about 222,357 (321)

Microglia-Derived Brain Macrophages Associate with Glioblastoma Stem Cells: A Potential Mechanism for Tumor Progression Revealed by AI-Assisted Analysis. [PDF]

Cells
Zheng Y, Fuse H, Alzoubi I, Graeber MB.
europepmc   +1 more source

Precision Stealth Nanofibers via PET‐RAFT Polymerisation: Synthesis, Crystallization‐driven Self‐assembly and Cellular Uptake Studies

Chemistry – A European Journal, EarlyView.
Stealth polymer nanofibers are promising therapeutic delivery systems that suffer from challenging functionalization. In this work we harness photoinduced electron/energy transfer reversible addition–fragmentation chain transfer (PET‐RAFT) polymerisation and crystallization‐driven self‐assembly (CDSA) to produce low length‐dispersity poly ...
Steven T. G. Street, Ekaterina Shteinberg, Juan Diego Garcia Hernandez, Hayley C. Parkin, Robert L. Harniman, Stephanie Willerth, Ian Manners   +6 more
wiley   +1 more source

Biomarkers in glioblastoma and degenerative CNS diseases: defining new advances in clinical usefulness and therapeutic molecular target. [PDF]

Front Mol Biosci
Bu F, Zhong J, Guan R.
europepmc   +1 more source

Epigallocathechin-3 Gallate Selectively Inhibits the PDGF-BB–induced Intracellular Signaling Transduction Pathway in Vascular Smooth Muscle Cells and Inhibits Transformation ofsis-transfected NIH 3T3 Fibroblasts and Human Glioblastoma Cells (A172)

, 1999
Hee‐Yul Ahn, Kourosch Reza Hadizadeh, Claudia Seul, Yeo‐Pyo Yun, H. Vetter, Agapios Sachinidis   +5 more
openalex   +2 more sources

Replacing a Cereblon Ligand by a DDB1 and CUL4 Associated Factor 11 (DCAF11) Recruiter Converts a Selective Histone Deacetylase 6 PROTAC into a Pan‐Degrader

ChemMedChem, EarlyView.
This study introduced DCAF11 as an E3 ligase for PROTAC‐mediated histone deacetylase (HDAC) degradation. By replacing cereblon with DCAF11 as recruited E3 ligase, a selective HDAC6 degrader (A6) was transformed into pan‐HDAC degraders. The lead compound, 1j (FF2039), potently degraded HDACs from classes I, IIa, and IIb, showing strong antiproliferative
Felix Feller, Heiko Weber, Martina Miranda, Irina Honin, Maria Hanl, Finn K. Hansen   +5 more
wiley   +1 more source

The intrinsic radioresistance of glioblastoma-derived cell lines is associated with a failure of p53 to induce p21 ^BAX expression

, 1998
Hui‐Kuo G. Shu, Moses M. Kim, Pengchin Chen, Felix Furman, Carol M. Julin, Mark A. Israel   +5 more
openalex   +1 more source

Neoadjuvant chemotherapy plus anlotinib in the treatment of resectable head and neck squamous cell carcinoma: A pilot phase II trial

Cancer Communications, EarlyView.
Qianting He, Shuojin Huang, Dongxiao Tang, Congyuan Cao, Wanhang Zhou, Rongsong Ling, Jie Chen, Bokai Yun, Xin Zheng, Yanchen Li, Anxun Wang, Demeng Chen   +11 more
wiley   +1 more source

Boron in My Mind: A Comprehensive Review of the Evolution of the Diverse Syntheses of 4‐Borono‐l‐Phenylalanine, the Leading Agent for Boron Neutron Capture Therapy

ChemMedChem, EarlyView.
Boron Neutron Capture Therapy is a promising technique for treating “untreatable” brain cancers by having 10B nuclei absorb neutrons and then decay to 7Li destroying the cells they are in. The dominant clinical agent is 4‐borono‐l‐phenylalanine, and this review comprehensively analyzes all of its reported patent and literature syntheses to help ...
Sarfraz Ahmad, Ming Pan, John J. Hayward, Massimo Sementilli, Lisa A. Porter, John F. Trant   +5 more
wiley   +1 more source