Results 271 to 280 of about 319,103 (346)

Intergenerational Enlargement of Human Organs as a Driver of Increased Cancer Risk?

open access: yesBioEssays, EarlyView.
Identifying the environmental factors and associated mechanisms driving increased cancer incidence in younger generations is a matter of great urgency. Here, we propose and discuss a new potential mechanism: larger organ sizes in younger individuals resulting from intergenerational differences in lifestyle, diet, and environmental exposures.
Costas Koufaris, Vicky Nicolaidou
wiley   +1 more source

A Positive Feedback DNA-PK/MYT1L-CXCR1-ERK1/2 Proliferative Signaling Loop in Glioblastoma. [PDF]

open access: yesInt J Mol Sci
Wang B   +7 more
europepmc   +1 more source

EpCAM and CD24 specific EVRNA analysis for ovarian cancer diagnosis

open access: yesBulletin of the Korean Chemical Society, EarlyView.
We developed a sensitive EV analysis technique by combination of immunomagnetic enrichment of tumor‐derived EVs with miRNA analysis. This technique offers over 88% diagnostic accuracy of ovarian cancer using only a single miRNA marker analysis of plasma EVs.
Yejin Kim   +11 more
wiley   +1 more source

Kinase-Targeted Therapies for Glioblastoma. [PDF]

open access: yesInt J Mol Sci
Salbini M   +4 more
europepmc   +1 more source

X‐ray controlled release strategy in cancer therapy

open access: yesBMEMat, EarlyView.
A comprehensive review on the design principles and current strategies of X‐ray stimulated release systems in cancer therapy, focusing on the X‐ray responsive functional groups and materials as well as discussing the advantages and current challenges of X‐ray controlled release systems in cancer therapy.
Yiling Ruan   +5 more
wiley   +1 more source

Unveiling the complexity of cellular senescence in cancers: From mechanism to therapeutic opportunities

open access: yesBMEMat, EarlyView.
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan   +12 more
wiley   +1 more source

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