Results 331 to 340 of about 319,103 (346)
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Asian Pacific Journal of Cancer Prevention, 2017
Glioblastoma multiforme (GBM) is one of the most malignant types of central nervous system tumors. Despite advances in treatment modalities it remains largely incurable.
F. Hanif +4 more
semanticscholar +1 more source
Glioblastoma multiforme (GBM) is one of the most malignant types of central nervous system tumors. Despite advances in treatment modalities it remains largely incurable.
F. Hanif +4 more
semanticscholar +1 more source
Current Treatment Options in Neurology, 2009
Optimal management of newly diagnosed glioblastoma multiforme includes maximal surgical resection, followed by 60 Gy of external beam radiation plus concomitant daily temozolomide and at least six additional monthly cycles of maintenance temozolomide.
Rose Lai, Mary Welch
openaire +3 more sources
Optimal management of newly diagnosed glioblastoma multiforme includes maximal surgical resection, followed by 60 Gy of external beam radiation plus concomitant daily temozolomide and at least six additional monthly cycles of maintenance temozolomide.
Rose Lai, Mary Welch
openaire +3 more sources
Gériatrie et Psychologie Neuropsychiatrie du Viellissement, 2011
The incidence of malignant gliomas is growing in the elderly population. Unfortunately, increasing age is one of the most important negative prognostic factors for gliomas, and the optimal management of this population remains largely unsettled because older patients are often excluded from clinical trials.
Florence Laigle-Donadey +1 more
openaire +3 more sources
The incidence of malignant gliomas is growing in the elderly population. Unfortunately, increasing age is one of the most important negative prognostic factors for gliomas, and the optimal management of this population remains largely unsettled because older patients are often excluded from clinical trials.
Florence Laigle-Donadey +1 more
openaire +3 more sources
2014
There is no generally agreed upon standard of care treatment for elderly patients (age ≥70 years) with glioblastoma (GBM). Treatment options range from supportive care only, radiation therapy (RT) only (most often given in a shortened hypofractionated schedule), temozolomide (TMZ) chemotherapy only, and the combination RT + TMZ, followed by post-RT TMZ
openaire +3 more sources
There is no generally agreed upon standard of care treatment for elderly patients (age ≥70 years) with glioblastoma (GBM). Treatment options range from supportive care only, radiation therapy (RT) only (most often given in a shortened hypofractionated schedule), temozolomide (TMZ) chemotherapy only, and the combination RT + TMZ, followed by post-RT TMZ
openaire +3 more sources
Anti-Cancer Agents in Medicinal Chemistry, 2015
This article focuses on the possible application of antagonists of the G-protein coupled chemokine receptor, CXCR4, for the treatment of glioblastoma and summarises the evidence for CXCR4 antagonism being a viable therapeutic approach. Particular attention is paid to the role of this receptor in cancer stem cell biology, and the maintenance of CXCR4 ...
openaire +3 more sources
This article focuses on the possible application of antagonists of the G-protein coupled chemokine receptor, CXCR4, for the treatment of glioblastoma and summarises the evidence for CXCR4 antagonism being a viable therapeutic approach. Particular attention is paid to the role of this receptor in cancer stem cell biology, and the maintenance of CXCR4 ...
openaire +3 more sources
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
Nature, 2012J. Schwartzentruber +64 more
semanticscholar +1 more source
Current state of immunotherapy for glioblastoma
Nature Reviews Clinical Oncology, 2018M. Lim +3 more
semanticscholar +1 more source
Mechanisms of immunotherapy resistance: lessons from glioblastoma
Nature Immunology, 2019Christopher M. Jackson +2 more
semanticscholar +1 more source