Results 181 to 190 of about 4,624,933 (258)

AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective

Advanced Intelligent Discovery, EarlyView.
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley   +1 more source

Induction of Methuosis in Breast Cancer Stem Cells by a Cobalt(III) Complex Evokes Immunotherapeutic Response

Angewandte Chemie, EarlyView.
Cancer stem cells (CSCs) drive metastasis, relapse and resist conventional apoptosis‐inducing chemotherapies. We report a cobalt(III)‐cyclam complex with pyrene and diflunisal moieties that reduces the viability of breast CSCs at low micromolar concentrations.
Jiaxin Fang, Sijie Wen, Xiao Feng, Hao Ren, Kuldip Singh, Haihua Xiao, Lingpu Zhang, Kogularamanan Suntharalingam   +7 more
wiley   +2 more sources

Graphene Oxide Modulates ROS Production and Apoptotic Responses to Bortezomib in Human Glioblastoma Cells: An In Vitro Study. [PDF]

Cells
Krętowski R, Jabłońska-Trypuć A, Tyszka N, Kalita J, Cechowska-Pasko M.   +4 more
europepmc   +1 more source

Spatially Informed Feature Selection and Machine Learning in Matrix‐Assisted Laser Desorption/Ionization Imaging for Cohort‐Scale Molecular Tissue Phenomics in Glioblastoma

Advanced Intelligent Discovery, EarlyView.
Matrix‐assisted laser desorption/ionization imaging‐based identification of reliable small molecule markers across heterogeneous glioblastoma cohorts is challenging with intensity‐only methods. We present spatially informed feature selection (SIFS), a spatially informed framework that prioritizes molecules consistently colocalizing with histopathology.
Shad A. Mohammed, Denis Abu Sammour, Dirk C. Hoffmann, Philipp Sievers, Tobias Bausbacher, Melissa Hahn, Yasemin Ucal, Iris Mildenberger, Christiane A. Opitz, Stefan Schmidt, Michael Platten, Oliver Wasenmüller, Wolfgang Wick, Andreas von Deimling, Tobias Kessler, Carsten Hopf   +15 more
wiley   +1 more source

Prodigiosin Enhanced TMZ Chemosensitivity by Suppressing Focal Adhesion and Inhibiting Autophagy in Glioblastoma Cells. [PDF]

Biomolecules
Dai S, Liu X, Jin X, Mo S, Li L, Wang C, Tian Y.   +6 more
europepmc   +1 more source

Growth Differentiation Factor 15 as a Cerebrospinal Fluid Biomarker for the Diagnosis and Prognosis of Leptomeningeal Metastasis

Annals of Neurology, EarlyView.
Objective As leptomeningeal metastasis (LM) has a poor prognosis, reliable cerebrospinal fluid (CSF) diagnostic biomarkers are urgently needed. This study evaluated the diagnostic value of CSF growth differentiation factor 15 (GDF15) in LM from lung adenocarcinoma (LUAD) and breast cancer (BC).
Haoyu Ruan, Jie Li, Fuhai Wang, Lei Zhang, Jie Luo, Yuan Mu, Ting Wang, Yuqing Wu, Jingping Liu, Yunyun Ning, Xuan Deng, Ming Guan, Jian Xu   +12 more
wiley   +1 more source

Overexpression of miR-219 as a potential therapeutic strategy of glioblastoma cells in vitro. [PDF]

Sci Rep
Petrović M, Lapčević S, Matić IZ, Bojić L, Nikitović M, Stanojković T, Stanisavljević Ninković D.   +6 more
europepmc   +1 more source

Synergistic In Vitro Effects of Minor Phytocannabinoids and Melatonin Combinations Against Human Glioblastoma Cells. [PDF]

Int J Mol Sci
Morelli MB, Cameli G, Giangrossi M, Zeppa L, Luongo M, Amantini C, Nabissi M.   +6 more
europepmc   +1 more source

Double functionalized Sindbis E2 glycoprotein modifies Sindbis tropism favouring infection of α5β1⁺ glioblastoma cells. [PDF]

Sci Rep
Duvergé A, Genty A, Kozmar L, Foppolo S, Lener D, Negroni M.   +5 more
europepmc   +1 more source

A Mussel-Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells. [PDF]

Adv Sci (Weinh)
Bolaños-Cardet J, Pugliese S, Bruna J, Ruiz-Molina D, Suárez-García S, Yuste VJ.   +5 more
europepmc   +1 more source