Results 331 to 340 of about 536,830 (388)

Taste Profile and Relative Bioavailability of Tovorafenib Powder for Oral Suspension and Food Effect of the Tovorafenib Tablet in Healthy Participants

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract A pediatric‐friendly powder for oral suspension (PfOS) of tovorafenib, a type II RAF inhibitor, was developed for patients with difficulty swallowing tablets. This open‐label, randomized, phase 1 study (QSC205140) evaluated the taste/palatability of PfOS formulations (n = 12), the relative bioavailability of the PfOS versus tablet formulation,
Yang Zhang   +6 more
wiley   +1 more source

APOBEC3C-Mediated NF-κB Activation Promotes Malignant Progression of Gliomas. [PDF]

open access: yesImmun Inflamm Dis
Zhang C   +6 more
europepmc   +1 more source

Seminars in epileptology: How to diagnose status epilepticus in adults and children

open access: yesEpileptic Disorders, EarlyView.
Abstract Status epilepticus (SE) can be regarded as the most severe expression of seizure activity characterized by a low probability of spontaneous cessation and mechanisms leading to metabolic and inflammatory derangements with increased risk of brain damage, alterations of neural networks, and potentially life‐threatening systemic complications ...
M. Leitinger   +12 more
wiley   +1 more source

Ictal semiology in anterior cingulate epilepsy: A systematic review

open access: yesEpileptic Disorders, EarlyView.
Abstract Seizures originating from the anterior cingulate cortex (ACC) have distinct clinical features but can be difficult to identify in frontal lobe epilepsy (FLE). This systematic review examines the key semiology of ACC seizures and their anatomical correlations.
Francine Chassoux   +6 more
wiley   +1 more source

A novel organoid model retaining the glioma microenvironment for personalized drug screening and therapeutic evaluation. [PDF]

open access: yesBioact Mater
Zheng C   +25 more
europepmc   +1 more source

Robust prediction of glioma prognosis by hypoxia-induced ferroptosis genes: VEGFA-XBP1 co-expression for salvage therapy. [PDF]

open access: yesCancer Biol Ther
Liwei Z   +12 more
europepmc   +1 more source

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