Results 71 to 80 of about 14,862,239 (364)
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
The contradictions of the Asian Monetary Fund [PDF]
, 2012 Focuses on the issue of an Asian Monetary Fund (AMF). At the time of its launch in March 2010, the Chiang Mai Initiative Multilateralisation (CMIM) was widely reported, particularly in Asia, as heralding the establishment of an AMF that would provide ...
Dixon, Chris, Global Policy Institute
core
Labyrinth: An International Journal for Philosophy, Value Theory and Sociocultural Hermeneutics, 2020 This paper uses Martin Luther and Mao Zedong's translation strategies to philosophize anew the dialectic between the national and the global in the history of revolutions.
Sinkwan Cheng
doaj
Remote Sensing, 2015 Timely and accurate information on the global cropland extent is critical for applications in the fields of food security, agricultural monitoring, water management, land-use change modeling and Earth system modeling.
François Waldner +3 more
doaj +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
Global Challenges, Global Opportunities
Annals of Global Health, 2014 Academia is at an exciting crossroads. The global problems we face are immense, but the good news is we know how to address most of them. Our primary challenge today is not a lack of knowledge but a failure to scale up what we already know works. Some of the skills to implement what we know are medical, many are not.
openaire +5 more sources
Global and local contributions to corneal surface curvature: a simple model
African Vision and Eye Health, 2008 Variations in corneal surface powers reflect variations in the geometry of the cornea. In particular one can regard corneal surface curvature as a combination of local and global effects.
W. F. Harris
doaj +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source