Results 71 to 80 of about 16,067,535 (312)
Six decades of global crop yield increase and cropland expansion from 1960 to 2020
Environmental Research CommunicationsPopulation growth, changing consumption preferences, technological advances, globalised trade and environmental influences have all shaped global agriculture.
Karina Winkler +3 more
doaj +1 more source
Frontiers in MicrobiologyIntroductionCarbapenem-resistant Pseudomonas aeruginosa (CRPA) represents a global threat, but the global distribution of carbapenem resistant bacteria remains a critical issue in public health.MethodsWe conducted a systematic review and meta-analysis on
Tsepo Ramatla +6 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Global burden and trends of self-harm from 1990 to 2021, with predictions to 2050
Frontiers in Public HealthBackgroundSelf-harm has become a major public health problem globally. Data on the burden of self-harm in this study were taken from the GBD 2021. This study aimed to quantify historical trends (1990–2021) in the global burden of self-harm across genders,
Li Xie +4 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Satellite Clear‐Sky Observations Overestimate Surface Urban Heat Islands in Humid Cities
Geophysical Research LettersSatellite‐based thermal infrared (TIR) land surface temperature (LST) is hindered by cloud cover and is applicable solely under clear‐sky conditions for estimating surface urban heat island intensity (SUHII).
Qiquan Yang +9 more
doaj +1 more source
Mental health phenotypes of well-controlled HIV in Uganda
Frontiers in Public HealthIntroductionThe phenotypic expression of mental health (MH) conditions among people with HIV (PWH) in Uganda and worldwide are heterogeneous. Accordingly, there has been a shift toward identifying MH phenotypes using data-driven methods capable of ...
Leah H. Rubin +15 more
doaj +1 more source
Global poverty & global politics [PDF]
, 2008 In recent years, many policymakers and scholars supportive of globalization – but opposed to many things done in the name of globalization – have begun to draw lessons from policymaking, statistical analysis and the lives of everyday citizens about what ...
VanDeveer, Stacy D.
core +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source