Results 81 to 90 of about 4,491,703 (310)

Mental health phenotypes of well-controlled HIV in Uganda

open access: yesFrontiers in Public Health
IntroductionThe phenotypic expression of mental health (MH) conditions among people with HIV (PWH) in Uganda and worldwide are heterogeneous. Accordingly, there has been a shift toward identifying MH phenotypes using data-driven methods capable of ...
Leah H. Rubin   +15 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Global Research Patterns In Islamic Finance: A Bibliometric Analysis

open access: yesIqtishaduna: Jurnal Ilmiah Ekonomi Kita
This study aims to map the gaps in understanding the direction of development in Islamic finance, trending topics, and areas that require further research.
Siti Ikmatul Munawaroh, Taufiqur Rahman
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A bright future in typhoid vaccines

open access: yesThe Lancet Global Health, 2021
The Lancet Global Health
doaj   +1 more source

Globalization [PDF]

open access: yesPrehospital and Disaster Medicine, 2006
openaire   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Global, regional, and national burden of spinal injuries attributable to road injuries: a systematic analysis of incidence, prevalence, and YLDs with projections to 2046

open access: yesFrontiers in Public Health
BackgroundRoad injuries remain a critical global public health issue, with spinal injuries representing a major contributor to long-term disability.
Yanqing Deng   +7 more
doaj   +1 more source

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