Results 151 to 160 of about 1,478,682 (342)
Background: Extreme poverty remains a persistent global challenge that limits access to essential services, including healthcare. In response, the Philippine government implemented the Pantawid Pamilyang Pilipino Program (4Ps), a conditional cash ...
Jeric Jamandre +4 more
doaj +1 more source
The Japan Aerospace Agency (JAXA) recently released multi-temporal global SAR mosaics derived from a 4-year data acquisition project (2007–2010) of the Advanced Land Observing Satellite (ALOS) PALSAR, L-band at 25 m spatial resolution. These open access data sets could assist traditional soil surveys and/or digital soil mapping programs undertaken at ...
del Valle, H +6 more
openaire +3 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Uganda’s Access to Global and Regional Markets
As a landlocked country in East Africa, Uganda faces two major disadvantages concerning access to foreign markets. It does not have an immediate gateway to low-cost ocean transport, but first has to pass its imports and exports through neighboring ...
Walkenhorst, Peter
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
The global shortage of neurointerventionalists presents a challenge to timely stroke care, particularly in low‐ and middle‐income countries. The Society of Vascular and Interventional Neurology Stroke Interventional Laboratory Consensus criteria aim to ...
Ossama Yassin Mansour +24 more
doaj +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
JHSPH scholar's program: strengthening the next generation of global tobacco control leaders
Background and challenges to implementation The Johns Hopkins Bloomberg School of Public Health (JHSPH) has supported a Global Tobacco Control Leadership Program and an academic Certificate Program for over a decade.
Joanna Cohen +2 more
core +1 more source

