Results 161 to 170 of about 1,478,682 (342)

Les mobiles du développement  : le téléphone portable comme outil d’empowerment des femmes des Suds ?

open access: yesTerminal
This article studies the emergence of the notion of empowerment as a category of development and its recent update in development programs that use the mobile phone as a central tool of action.
Marine Al Dahdah
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

The case for "Open Access" communications infrastructure in Africa : the SAT-3/WASC cable - a briefing

open access: yes, 2008
This study examines the impact the SAT-3 fibre optic submarine cable has had on telecommunications in four African countries has found that the potential of the cable has not been properly exploited. Instead, ownership of the cable by telecoms incumbents
Jagun, A.
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

CDC Division of Global HIV & TB country profile : Jamaica

open access: yes
The U.S. Centers for Disease Control and Prevention (CDC) office in Jamaica serves as a regional hub for CDC\u2019s Caribbean Regional Office (CRO) which also provides direct support to Guyana, and Trinidad and Tobago.

core   +2 more sources

CDC Division of Global HIV & TB country profile : Nigeria

open access: yes
Active Strategic Scale-up of Comprehensive HIV Services: The U.S. Centers for Disease Control and Prevention (CDC) Nigeria office was established in February 2001, providing technical leadership and assistance to the Federal Ministry of Health (MOH) and ...

core   +2 more sources

Working Towards a Decolonized, Longitudinal, and Equitable Global Health Training and Partnerships Program

open access: yesJournal of Medical Education and Curricular Development
OBJECTIVES Growth of global health education programs has blossomed over the past two decades in the United States; yet many do not address the roots of colonialism and racism in medicine. This paper highlights the Arrupe Global Scholars and Partnerships
Jason Beste   +6 more
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Our changing planet : the Fiscal Year 2003 U.S. Global Change Research Program and Climate Change Research Initiative : a report /

open access: yes, 2002
Mode of access ...
Climate Change Science Program (U.S.)   +1 more
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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