Results 121 to 130 of about 4,951,195 (308)
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller +14 more
wiley +1 more source
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma +16 more
wiley +1 more source
Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova +9 more
wiley +1 more source
Asymptotic structure of time-dependent global attractors for the nonclassical diffusion equations
Nonclassical reaction-diffusion equations mainly stem from non-Newtonian flows, solid mechanics, and heat conduction theories. The longtime behavior and asymptotic structure of solutions to these equations are important. We study the asymptotic structure
WANG Xiao-Ping, MA Qiao-Zhen
doaj
Long‐Term Neurologic Exam Findings in People Diagnosed and Treated During Acute HIV Infection
ABSTRACT Objective Evaluate clinical and laboratory correlates of abnormal neurologic exam findings after acute HIV infection (AHI). Methods Participants from the RV254/SEARCH 010 cohort in Bangkok underwent standardized neurologic examinations at Weeks 0 (AHI), 12, 96, and 288 following antiretroviral therapy (ART).
Kathryn B. Holroyd +118 more
wiley +1 more source
Generating Fully Bounded Chaotic Attractors
Generating chaotic attractors from nonlinear dynamical systems is quite important because of their applicability in sciences and engineering. This paper considers a class of 2-D mappings displaying fully bounded chaotic attractors for all bifurcation ...
Zeraoulia Elhadj
core +1 more source
Global attractors of non-autonomous quasi-homogeneous dynamical systems
It is shown that non-autonomous quasi-homogeneous dynamical systems admit a compact global attractor. The general results obtained here are applied to differential equations both in finite dimensional spaces and in infinite dimensional spaces, such as ...
David N. Cheban
doaj
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu +7 more
wiley +1 more source
Regular attractors and nonautonomous perturbations of them
We study regular global attractors of dissipative dynamical semigroups with discrete or continuous time and we investigate attractors for nonautonomous perturbations of such semigroups.
Chepyzhov, VV, Zelik, SV, Vishik, MI
core +1 more source

