Results 171 to 180 of about 5,050,575 (301)

Type I Interferon Drives Dysfunction of a Distinct CD8+ HLA‐DRB1+ T Cell Subset in Systemic Lupus Erythematosus

Arthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) is characterized by type I interferon (IFN) signaling and adaptive immune dysregulation. We previously identified hypomethylation of HLA‐DRB1 and STAT1 in SLE CD8+ T cells, enabling aberrant IFN‐driven HLA‐DRB1 expression and expansion of a distinct CD8+ T cell subset. This study characterized CD8+ HLA‐DRB1+
Huizhong Long, Elio Carmona, Mikhail G. Dozmorov, Amr H. Sawalha   +3 more
wiley   +1 more source

Dynamic Landscape Analysis of cell fate decisions provides predictive models of neural development from single-cell data. [PDF]

PLoS Biol
Fontaine M, Delás MJ, Sáez M, Maizels RJ, Finnie E, Briscoe J, Rand DA.   +6 more
europepmc   +1 more source

The hows and whys—A new teaching model for anatomy learning supported by customized 3D printed models

Anatomical Sciences Education, EarlyView.
Abstract The advent of three‐dimensional (3D) printing technology has enabled educators to design customized 3D printed models (3DPMs), but the current literature shows conflicting evidence regarding the impact of 3DPMs on students' knowledge acquisition.
Rocky Chun Chung Cheung, Tomasz Cecot, Susan M. Bridges, George L. Tipoe, Jian Yang   +4 more
wiley   +1 more source

Stability and Hopf bifurcation analysis of a fractional-order Filippov prey-predator model with prey refuge and fear effects. [PDF]

Sci Rep
Nadeem M, Ramesh P, Sambath M, Alsayaad Y.   +3 more
europepmc   +1 more source

Direct SMBH Formation Driven by Runaway Stellar Collisions in Globally Unstable Stellar Systems

Astronomische Nachrichten, EarlyView.
ABSTRACT The fueling problem addresses the ultimate fate of the reservoirs of gas and stars driven into the deepest gravitational potential wells of galaxies, thus it may contain the Universe's densest concentrations of gas and stars. This raises a key question: does the infalling material collapse directly into a supermassive black hole, or can it ...
Marcelo C. Vergara, Andrés Escala
wiley   +1 more source

Detailed study of bifurcations in a rate model with excitatory and inhibitory neurons and adaptation. [PDF]

J Comput Neurosci
Windisch A, Simon PL.
europepmc   +1 more source

The Preprint Evolution: The Rise of Unreviewed Drafts on arXiv and Its Implications for Astronomy

Astronomische Nachrichten, EarlyView.
ABSTRACT The arXiv preprint server originally democratized astronomical research by removing the financial barriers of journal subscriptions. However, a system designed for the lower publication volumes of the 1990s has fractured under modern research output. Today, the sheer volume of unreviewed manuscripts—often tagged as “submitted,” “under review,”
Luigi Rolly Bedin
wiley   +1 more source

Modeling parasite clearance and transmission delays in American Cutaneous Leishmaniasis transmission dynamics. [PDF]

J Math Biol
Sultana S, Gonzalez-Parra G, Chaves LF.
europepmc   +1 more source

Low‐Field MRI as a Multiparametric Tool for Large Engineered Tissue Characterization

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Advances in 3D bioprinting have enabled the fabrication of large and complex engineered tissues, but their increasing size demands non‐invasive tools for monitoring structure, maturation, and perfusion. Magnetic Resonance Imaging (MRI) offers unique multiparametric capabilities, yet high‐field systems remain costly and inaccessible for most ...
Yilbert Gimenez, Valernst Martial Gilmus, Elliott Cowles, Lucie Essayan, Vincent Semet, Michel Cabrera, Christophe A. Marquette, Simon A. Lambert, Emma Petiot   +8 more
wiley   +1 more source

Case Report: Intravascular lithotripsy combined with a new-generation 3-in-1 carotid stent for calcified carotid artery stenosis. [PDF]

Front Surg
Ertl WJP, Verma U, Shakir HJ, Jen S.
europepmc   +1 more source