Results 211 to 220 of about 4,759,858 (314)

Local patient-centered headache advocacy with regional and global impact: lessons from the Japanese Patient Advocacy Coalition (JPAC). [PDF]

J Headache Pain
Danno D, Yamanaka E, Tabata K, Kikui S, Chu MK, Begasse de Dhaem O, Hirata K, Sakai F, Takeshima T.   +8 more
europepmc   +1 more source

Global Center of Excellence Review

Journal of the Japan Society for Precision Engineering, 2014
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Hierarchical deep learning pipeline for robust cervical parameter measurement in radiographs with C7 obscuration. [PDF]

NPJ Digit Med
Kang DH, Park SJ, Park JS, Park H, Lee CS.   +4 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Transient Global Amnesia After Screening Esophagogastroduodenoscopy: Incidence and Risk Factors in a 20-Year Single-Center Cohort. [PDF]

DEN Open
Kobayashi M, Takayama I, Ohtaka M, Ishida Y, Hihara Y, Miura M, Hosoda K, Hirose Y, Takaso K, Yoda Y, Kobayashi F, Yokomichi H, Enomoto N.   +12 more
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Landscape of diabetic kidney disease drug clinical trials in China (2013-2023): global implications for innovation and policy. [PDF]

Ren Fail
Yang Y, Tan H, Xiao Z, Zhu J, Chen Y, Li G.   +5 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Accelerated north-east shift of the global green wave trajectory. [PDF]

Proc Natl Acad Sci U S A
Mahecha MD, Kraemer G, Reinhardt M, Montero D, Gans F, Bastos A, Feilhauer H, Flik I, Ji C, Kattenborn T, Migliavacca M, Mönks M, Quaas J, Sippel S, Walther S, Wieneke S, Wirth C, Camps-Valls G.   +17 more
europepmc   +1 more source