Results 201 to 210 of about 6,655,877 (292)

Genomic Evidence for Local Adaptation to Elevation and Climate Sheds New Light on Variable Responses to Global Change in American Pikas (Ochotona princeps). [PDF]

Mol Ecol
Beever EA, Osterhoudt E, Linck EB.
europepmc   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Plant traits and associated ecological data from global change experiments and climate gradients in Norway. [PDF]

Sci Data
Vandvik V, Halbritter AH, Macias-Fauria M, Maitner BS, Michaletz ST, Telford RJ, Bison N, Chacon-Labella J, Cotner S, Egelkraut D, Garen J, Gaudard J, Geange SR, Rosati MA, Andersen EAS, Ahler SJ, Atkinson J, Baumane M, Bradler PM, Dawson HR, Eckberg J, Elsy AD, Erkelenz J, Eshelman SE, Guclu C, Gullvåg R, Gya R, Hartford S, Hayden MT, Holle MJM, Kullberg AT, Lepley K, Correia M, Löwenstein CE, Maré C, Mauki D, Navarro J, Oberholzer B, Olivier B, Olson AN, Ray CA, von Oppen J, Vorstenbosch T, Wang JA, Enquist BJ.   +44 more
europepmc   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Soil microbial responses to multiple global change factors as assessed by metagenomics. [PDF]

Nat Commun
Rodríguez Del Río Á, Scheu S, Rillig MC.   +2 more
europepmc   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Complementary genetic and epigenetic changes facilitate rapid adaptation to multiple global change stressors. [PDF]

Proc Natl Acad Sci U S A
Brennan RS, deMayo JA, Finiguerra M, Baumann H, Dam HG, Pespeni MH.   +5 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Linking species distribution and chemistry to support the management of Saposhnikovia divaricata under global change. [PDF]

Sci Rep
Duan D, Li X, Zhou X, Xu H, Chen J, Zhang B, Zhang X.   +6 more
europepmc   +1 more source