Results 201 to 210 of about 12,171,189 (307)

Biological traits predict species' time-varying responses to multiple global change drivers. [PDF]

Nat Commun
Sasaki T, Iwachido Y, Lam-Gordillo O, Cook KM, Douglas EJ, Gladstone-Gallagher RV, Greenfield B, Hailes S, Carter K, Ishii NI, Takayama Y, Shimode S, Kagami M, Hewitt JE, Thrush SF, Lohrer AM.   +15 more
europepmc   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Congo Basin Carbon Cycle Responses to Global Change. [PDF]

Glob Chang Biol
Worden S, Fu R, Bloom AA, Bauters M, Verbeeck H, Fatoyinbo T, Hubau W, Koutika LS, Kengdo SK, Maes SL, Medjibe V, Russo NJ, Saatchi S, Sagang LB, Smith TB, Sonwa DJ, Boeckx P, Ordway EM.   +17 more
europepmc   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Global Change and Cognition.

, 2013
Lewandowsky, Stephan, Lombrozo, Tania, Brown, Gordon, Cook, John, Newell, Ben, Ecker, Ullrich   +5 more
openaire   +2 more sources

Author Correction: Public support for carbon pricing policies and revenue recycling options: a systematic review and meta-analysis of the survey literature

npj Climate Action
Farah Mohammadzadeh Valencia, Cornelia Mohren, Anjali Ramakrishnan, Marlene Merchert, Jan C. Minx, Jan Christoph Steckel   +5 more
doaj   +1 more source

Contrasting vulnerability profiles for insular assemblages of birds and mammals facing global change. [PDF]

Conserv Biol
Marino C, Benítez-López A, Butt N, Caetano G, Capdevila P, Denelle P, Etard A, Fernández Palacios JM, Ferreiro-Arias I, Leclerc C, Lenoir J, Philippe-Lesaffre M, Rigal F, Bellard C.   +13 more
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Advancing the science of systemic environmental risk in an era of global change. [PDF]

Fundam Res
Wang G, Cao S, Wu J.
europepmc   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source