Results 231 to 240 of about 12,171,189 (307)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Identifying and addressing the anthropogenic drivers of global change in the North Sea: a systematic map. [PDF]

Environ Evid
Blöcker AM, Auch D, Gutte HM, Biederbick J, Asselot R, Färber L, Börner G, Kamberi E, Madiraca F, Ofelio C, Steidle L, Moullec F.   +11 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Tree diversity is changing across tropical Andean and Amazonian forests in response to global change. [PDF]

Nat Ecol Evol
Fadrique B, Costa F, Cuesta F, Arellano G, Cayuela L, Baker TR, Draper FC, Esquivel-Muelbert A, Ter Steege H, Bauters M, Aguirre-Gutiérrez J, Aguirre-Mendoza Z, Alexiades MN, Alvarez-Davila E, Arets E, Ayala E, Aymard CGA, Baccaro F, Báez S, Baraloto C, Barbosa RI, Barbosa Camargo P, Barlow J, Barni PE, Barroso J, Benchimol M, Bennett AC, Berenguer E, Blanc L, Bonal D, Bongers F, Brienen R, Brown F, Bt Andrade M, Burban B, Burnham RJ, Camargo JL, Carvalho SPC, Castilho C, Chave J, Coelho de Souza F, Comiskey J, da Costa L, de Lima RB, de Oliveira EA, de Oliveira RLC, de Oliveira Perdiz R, De Rutte J, Del Aguila-Pasquel J, Derroire G, Di Fiore A, Disney M, Duque A, Emilio T, Farfan-Rios W, Fauset S, Fearnside PM, Feeley KJ, Feldpausch TR, Ferreira J, Ferreira L, Flores Llampazo GR, Galbraith D, García-Cabrera K, García Criado M, Gloor E, Grandez-Rios JM, Hérault B, Homeier J, Honorio Coronado EN, Huamantupa-Chuquimaco I, Huaraca Huasco W, Huillca-Aedo YT, Idárraga Á, Jadán-Maza O, Kalamandeen M, Killeen TJ, Laurance SGW, Laurance WF, Levesley A, Lopez W, Macía MJ, Magnusson WE, Malhi Y, Manzatto AG, Marimon BS, Marimon Junior BH, Martínez-Villa JA, Medeiros MB, Melgaço K, Melo L, Metzker T, Monteagudo A, Morandi PS, Myers JA, Nascimento HM, Nascimento R, Neill D, Nieto-Ariza B, Palacios WA, Palacios-Ramos S, Pallqui-Camacho NC, Pardo Molina G, Peacock J, Peña MA, Pennington RT, Peñuela MC, Peres CA, Pérez ÁJ, Pickavance GC, Pinto E, Pipoly J, Pitman N, Prieto A, Ramírez-Angulo H, Reis SM, Restrepo Z, Reynel C, Ribeiro S, Rivas-Torres G, Rojas R, Rudas A, Salinas N, Salomão RP, Santana F, Schietti J, Schwartz G, Serrano J, Silman M, Silva C, Silva CA, Silva RC, Silva RSA, Silva-Espejo J, Silveira M, Simon MF, Soto-Shareva YC, Souza PF, Storck-Tonon D, Stropp J, Swamy V, Tello JS, Terborgh J, Thomas R, Torres-Lezama A, Vale JD, Valenzuela Gamarra L, van der Heijden G, van der Hout P, van der Meer PJ, Vasquez Martinez R, Vedovato L, Verbeeck H, Vieira I, Vieira SA, Vilanova E, Vinceti B, Vos VA, Zagt R, Zuidema PA, Phillips OL.   +160 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Overcoming barriers to build partnerships for managing plant invasions under global change. [PDF]

Conserv Biol
Bufford JL, Brandt AJ, Chong KY, Hooper A, Kamelamela KL, Martin C, Parker IM, Pauchard A, Suding KN, Peltzer DA.   +9 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Correction: From microbiome collapse to recovery: a roadmap for microbiome-informed grassland restoration under global change. [PDF]

Front Microbiol
Qiao X, Yan X, Dong C, Tao L, Aili A, Waheed A.   +5 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Interepidemic Rift Valley fever in East Africa: the recent risk landscape and projected impacts of global change. [PDF]

Proc Biol Sci
Eskew EA, Clancey E, Singh D, Situma S, Nyakarahuka L, Njenga MK, Nuismer SL.   +6 more
europepmc   +1 more source