Results 241 to 250 of about 6,720,476 (300)

Functional diversity shapes the stability of reef fish biomass under global change. [PDF]

open access: yesProc Biol Sci
Mahaut L   +10 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha   +4 more
wiley   +1 more source

Connecting the dots: Managing species interaction networks to mitigate the impacts of global change. [PDF]

open access: yesElife
Abdala-Roberts L   +12 more
europepmc   +1 more source

Trophic Interactions Are Key to Understanding the Effects of Global Change on the Distribution and Functional Role of the Brown Bear. [PDF]

open access: yesGlob Chang Biol
Lucas PM   +86 more
europepmc   +1 more source

Dryland fungi are spatially heterogeneous and resistant to global change drivers. [PDF]

open access: yesEcosphere
Lopez A   +7 more
europepmc   +1 more source

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