Results 61 to 70 of about 2,061,932 (305)

Participation in the global knowledge commons : challenges and opportunities for research dissemination in developing countries [PDF]

open access: yes, 2004
Due to improving Internet connectivity and a growing number of international initiatives, knowledge workers in developing countries are now getting access to scholarly and scientific publications and electronic resources at a level that is unmatched ...
Chan, Leslie, Costa, Sely
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Reports of coal’s terminal decline may be exaggerated

open access: yesEnvironmental Research Letters, 2018
We estimate the cumulative future emissions expected to be released by coal power plants that are currently under construction, announced, or planned. Even though coal consumption has recently declined and plans to build new coal-fired capacities have ...
Ottmar Edenhofer   +3 more
doaj   +1 more source

Status consciousness in energy consumption: a systematic review

open access: yesEnvironmental Research Letters, 2021
Access to energy is a precondition for a decent standard of living. Some household decisions on energy consumption are however motivated to maintain or improve status, resulting in social zero-sum games, with environmentally harmful outcomes.
Anjali Ramakrishnan, Felix Creutzig
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

The role of capital costs in decarbonizing the electricity sector

open access: yesEnvironmental Research Letters, 2016
Low-carbon electricity generation, i.e. renewable energy, nuclear power and carbon capture and storage, is more capital intensive than electricity generation through carbon emitting fossil fuel power stations.
Lion Hirth, Jan Christoph Steckel
doaj   +1 more source

Secure robust carbon dioxide removal policy through credible certification

open access: yesCommunications Earth & Environment, 2023
Carbon Dioxide Removal (CDR) is a key element of any mitigation strategy aiming to achieve the long-term temperature goal of the Paris Agreement, as well as national net-zero and net-negative greenhouse gas emissions targets.
Felix Schenuit   +10 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

UNDERSTANDING THE GLOBAL COMMONS [PDF]

open access: yes
We want to clarify the way in which we think about the global commons, particularly the problem of global warming caused by greenhouse gas emissions and tropical deforestation.
Bromley, Daniel W., Cochrane, Jeffrey A.
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

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