Results 51 to 60 of about 5,994,810 (305)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Handbook of Belgian Competition Law. Anticompetitive practices
, 2021 Le Manuel de droit belge de la concurrence présente le droit belge des pratiques restrictives de concurrence : • le Chapitre I porte sur le droit des ententes entre entreprises : cartels, accords de coopération horizontale et accords verticaux ; • le ...
Neyrinck, Norman
core
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
THE IMPACT OF GLOBAL COMPETITION ON THE STATE OF MANUFACTURING IN UKRAINE AND DEVELOPED COUNTRIES
Baltic Journal of Economic Studies, 2017 At the end of the 20th century, the economic structure was changed fundamentally in some countries. It was mostly related to the growth of global competition.
Kateryna Shatnenko
doaj
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Changing Identities. From DiverseyLever to JohnsonDiversey: a Case of Cultural Integration
Symphonya, 2002 The Diversey acquisition from the Unilever group was official the 1st April 1996. The final aim of this operation consisted in a merger between the new acquired company and Industrial Lever to create a new world leader reality in the industrial cleaning
Liberato Angellotti +3 more
doaj +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
The Creation of a Champagne Brand
Symphonya, 2015 The history of Champagne Encry is marked by the courage and the strong desire to embark on a journey that makes us unique in the world of Champagne. The art of making Champagne has grown together with the value of our wines and merged wisely with the ...
Enrico Baldin
doaj +1 more source
Global vs. local competition [PDF]
, 2003 info:eu-repo/semantics ...
Legros, Patrick, Stahl, Konrad
openaire +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source