Results 71 to 80 of about 6,021,261 (305)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

An updated definition of global health

open access: yes
The most cited definition of global health, published in The Lancet in 2009, defines global health as "an area for study, research, and practice that places a priority on improving health and achieving equity in health for all people worldwide".
Waggett, Caryl E.   +15 more
core   +1 more source

EXPRESSIVE MEANS OF CONTEMPORARY RUSSIAN ANIMATION / БЫЛИННЫЙ ЭПОС В СОВРЕМЕННОЙ ОТЕЧЕСТВЕННОЙ АНИМАЦИИ

open access: yesНаука телевидения, 2016
The article focuses on the processes of modern domestic animatography, associated with changes in the figurative language, the appearance of new forms of storytelling. The author shows that a number of commercial projects based on folk traditions, is not
GORDIYENKO Y.S. / ГОРДИЕНКО Я.C.
doaj  

Demand Bubbles, Virtual Communities and Market Potential

open access: yesSymphonya, 2003
A virtual community is a precious information collation source allowing a company to identify conditions on which to base bubble information and indications regarding the time and manner on which the bubble should be triggered.
Flavio Gnecchi, Margherita Corniani
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

The Distinction Between in Cloud Computing of Small and Medium-Sized Enterprises in The Field of E-commerce [PDF]

open access: yesKošická bezpečnostná revue
This study explores the nuanced landscape of cloud computing adoption within small and medium-sized enterprises (SMEs) operating in the dynamic field of e-commerce.
Görkem GÖK
doaj  

Ouverture de ‘IR 4.0, Network Economies & Stakeholder Engagement’

open access: yesSymphonya, 2019
Global corporations operate today in conditions of highly competitive tension in a context subject to political, social and technological instability. In recent years, the Greek economic crisis of 2009 showed the new basic drivers of global capitalism ...
Silvio M. Brondoni, Paolo Boccardelli
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Competition and the State

open access: yes, 2014
Competition and the State analyzes the role of the state across a number of dimensions as it relates to competition law and policy across a number of dimensions.

core  

Shareowners, Stakeholders & the Global Oversize Economy. The Coca-Cola Company Case

open access: yesSymphonya, 2019
Since 2010, globalisation has imposed a new view of the competitive environment in which competitors are not always direct rivals. On the contrary, as a result of alliances and agreements, certain firms can become mega-organisations that have the ...
Silvio M. Brondoni
doaj   +1 more source

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