Results 31 to 40 of about 6,852 (218)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

International Competitive Disposition of National Higher Education Systems [PDF]

open access: yesInternational Economic Policy, 2017
In this paper, the stratification of national systems of higher education in a dynamic competitive environment, which is one of the ways of deepening the asymmetries of global economic development, is examined. Governments of key innovation countries,
Antonyuk Larysa   +3 more
doaj  

Management Control in Global Mass Market Retailers

open access: yesSymphonya, 2010
For large retail firms, management control is a valid tool with which to face the competition of global markets and to manage corporate complexity.
Francesca Gennari
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

EDLP and Private Labels: Unes Strategic Levers to Look Forward

open access: yesSymphonya, 2015
U2 Supermarket and private label products are the main strategic levers that qualify the development of UNES. U2 is a "countercurrent Supermarket” that combine the Every Day Low Price (EDLP) business model with the offer of a wide range of private label ...
Paolo Paronzini
doaj   +1 more source

Technology management in global competition and competitive advantage

open access: yesPressacademia, 2017
Technology is a major factor for success in the global competitive environment. In today's world, by technological development, competition become more intense and new opportunities arise. Obtaining an advantageous position in the global competitive environment depends on satisfying consumer demands with best quality at an affordable cost.
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Innovation and Imitation: Corporate Strategies for Global Competition

open access: yesSymphonya, 2012
In open markets where competition is strong, innovation loses its role of ‘ideological hierarchy’ over imitation; both have the common goal of maximising company profitability, with the constraint of optimising performance results in the very short term.
Silvio M. Brondoni
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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