Results 71 to 80 of about 176,455 (267)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

A New Industrial Policy for the Italian Start-Up Ecosystem

open access: yesSymphonya, 2015
Since 2012 the Italian Government has been engaged in the creation of a far-reaching legislative package aimed at supporting the development of the national start-up ecosystem.
Roberto Volpe, Mattia Corbetta
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

EXPRESSIVE MEANS OF CONTEMPORARY RUSSIAN ANIMATION / БЫЛИННЫЙ ЭПОС В СОВРЕМЕННОЙ ОТЕЧЕСТВЕННОЙ АНИМАЦИИ

open access: yesНаука телевидения, 2016
The article focuses on the processes of modern domestic animatography, associated with changes in the figurative language, the appearance of new forms of storytelling. The author shows that a number of commercial projects based on folk traditions, is not
GORDIYENKO Y.S. / ГОРДИЕНКО Я.C.
doaj  

Demand Bubbles, Virtual Communities and Market Potential

open access: yesSymphonya, 2003
A virtual community is a precious information collation source allowing a company to identify conditions on which to base bubble information and indications regarding the time and manner on which the bubble should be triggered.
Flavio Gnecchi, Margherita Corniani
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

The Distinction Between in Cloud Computing of Small and Medium-Sized Enterprises in The Field of E-commerce [PDF]

open access: yesKošická bezpečnostná revue
This study explores the nuanced landscape of cloud computing adoption within small and medium-sized enterprises (SMEs) operating in the dynamic field of e-commerce.
Görkem GÖK
doaj  

Ouverture de ‘IR 4.0, Network Economies & Stakeholder Engagement’

open access: yesSymphonya, 2019
Global corporations operate today in conditions of highly competitive tension in a context subject to political, social and technological instability. In recent years, the Greek economic crisis of 2009 showed the new basic drivers of global capitalism ...
Silvio M. Brondoni, Paolo Boccardelli
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Shareowners, Stakeholders & the Global Oversize Economy. The Coca-Cola Company Case

open access: yesSymphonya, 2019
Since 2010, globalisation has imposed a new view of the competitive environment in which competitors are not always direct rivals. On the contrary, as a result of alliances and agreements, certain firms can become mega-organisations that have the ...
Silvio M. Brondoni
doaj   +1 more source

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