Results 61 to 70 of about 6,021,261 (305)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Changing Identities. From DiverseyLever to JohnsonDiversey: a Case of Cultural Integration

open access: yesSymphonya, 2002
The Diversey acquisition from the Unilever group was official the 1st April 1996. The final aim of this operation consisted in a merger between the new acquired company and Industrial Lever to create a new world leader reality in the industrial cleaning
Liberato Angellotti   +3 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

International Competition Policy Advisory Committee: Antitrust Division

open access: yes, 1998
The International Competition Policy Advisory Committee (ICPAC) was formed in November 1997 to address the global antitrust problems of the 21st ...
DOJ/ATR International Competition Policy Advisory Committee
core  

The Creation of a Champagne Brand

open access: yesSymphonya, 2015
The history of Champagne Encry is marked by the courage and the strong desire to embark on a journey that makes us unique in the world of Champagne. The art of making Champagne has grown together with the value of our wines and merged wisely with the ...
Enrico Baldin
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

From Local to Global Competition [PDF]

open access: yes
This paper lays out and elaborates upon the properties of an extended Chamberlinian model with applications both in Industrial Organization and Economic Geography/ Urban Economics.
Simon P. Anderson, Andre de Palma
core  

Ouverture de ‘Special Issue on Fashion and Luxury Management’

open access: yesSymphonya, 2015
In 2014, the luxury fashion market closed with a value of 224 billion euros marking a growth at constant exchange rates of 3 percent and driven primarily by the online channel, and the outlet one.
Silvio M. Brondoni, Elisa Arrigo
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

A New Industrial Policy for the Italian Start-Up Ecosystem

open access: yesSymphonya, 2015
Since 2012 the Italian Government has been engaged in the creation of a far-reaching legislative package aimed at supporting the development of the national start-up ecosystem.
Roberto Volpe, Mattia Corbetta
doaj   +1 more source

Home - About - Disclaimer - Privacy