Results 51 to 60 of about 6,021,261 (305)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Competition in evolving communications markets: issues paper [PDF]

open access: yes, 2016
The Australian Competition and Consumer Commission (ACCC) has commenced a market study to examine a range of interrelated matters that have been raised by the industry that may affect the development of competition and efficiency in communications ...
Australian Competition and Consumer Commission
core  

Impact of Global Economic Challenges on the Development of Future Markets

open access: yesЭкономика и управление, 2019
The topic of the study is relevant due to the fact that the world economy and international economic relations are influenced by global challenges. In this context, the formation of a new technological paradigm based on digitalization is an important ...
Yu. G. Lavrikova   +3 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Handbook of Belgian Competition Law. Anticompetitive practices

open access: yes, 2021
Le Manuel de droit belge de la concurrence présente le droit belge des pratiques restrictives de concurrence : • le Chapitre I porte sur le droit des ententes entre entreprises : cartels, accords de coopération horizontale et accords verticaux ; • le ...
Neyrinck, Norman
core  

THE IMPACT OF GLOBAL COMPETITION ON THE STATE OF MANUFACTURING IN UKRAINE AND DEVELOPED COUNTRIES

open access: yesBaltic Journal of Economic Studies, 2017
At the end of the 20th century, the economic structure was changed fundamentally in some countries. It was mostly related to the growth of global competition.
Kateryna Shatnenko
doaj  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Global vs. local competition [PDF]

open access: yes, 2003
info:eu-repo/semantics ...
Legros, Patrick, Stahl, Konrad
openaire   +1 more source

Global competition in health care [PDF]

open access: yesBMJ, 1996
Your software may come from the United States, your computer from Singapore, your car from Germany or Japan, and your wine from Chile, but no matter where you are reading this your health care is probably provided from your own country. That may be about to change, particularly if you live in the developing world.
openaire   +2 more sources

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