Results 101 to 110 of about 12,041,342 (342)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Global Networks, Knowledge Management and World Cities

open access: yesSymphonya, 2011
Global markets are revolutionising the basic concepts of research, manufacturing and marketing, and developing corporate networks based on competitive alliances.
Silvio M. Brondoni
doaj   +1 more source

Competition on the Global Market: A Way Towards an Autonomous International Court for Global Competition Cases [PDF]

open access: yes
Competition policy is a field where economists and lawyers have to work hand in hand to achieve efficiency and, in the international arena, global welfare.
Alen Balde
core  

GCode For Siemens Competition

open access: yes, 2017
<p>For Siemens Science Competition</p> ...
Competition Entrant   +1 more
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Intangibles, Global Networks & Corporate Social Responsibility

open access: yesSymphonya, 2010
Network organisations emphasise the importance of corporate and product intangible assets. In global competition, the managerial economics of intangibles imposes new network policies of corporate social responsibility, dominated by global social issues ...
Silvio M. Brondoni
doaj   +1 more source

Global stability and pattern formation in a nonlocal diffusive Lotka–Volterra competition model

open access: yesJournal of Differential Equations, 2018
A diffusive Lotka–Volterra competition model with nonlocal intraspecific and interspecific competition between species is formulated and analyzed. The nonlocal competition strength is assumed to be determined by a diffusion kernel function to model the ...
W. Ni, Junping Shi, Ming-Xin Wang
semanticscholar   +1 more source

Impact of Globalization on Model of Competition and Companies’ Competitive Situation [PDF]

open access: yes, 2012
Globalization has changed the competitive environment of companies. This paper aims to contribute to understanding the changes a company can face through analyzing the impact of drivers and effects of globalization on the models of industry competition and the company value chain.
Knut Erik Bang, Tore Markeset
openaire   +3 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

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