Results 51 to 60 of about 8,665,882 (252)

Human capital in the competitive advantages determinants system in terms of territories sustainable development [PDF]

BIO Web of Conferences
The features of the human capital development in the competitive advantages determinants system of the Russian Federation economy in the conditions of territories sustainable development had been identified.
Shilets Elena S., Dmytrychenko Liliya I., Kravchenko Victoria A., Sokrutenko Olga-Anna S., Klochkova Oksana V.   +4 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Paths to Global Competitiveness

Recoletos Multidisciplinary Research Journal, 2014
The study focuses on generating the paths that would model the effects of six predictors on competitiveness. These predictors are innovation, human development, Information and Communications Technology(ICT), Research and Development (R&D), population ...
Josephine E. Petralba
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

UK Competitiveness Index 2019 [PDF]

, 2019
First introduced and published in 2000, this UK Competitiveness Index (UKCI) represents the 2019 edition of the report. The UKCI provides a benchmarking of the competitiveness of the UK’s localities2 , and it has been designed to be an integrated measure
Prokop, D, Huggins, R, Huggins, Robert, Thompson, P, Thompson, Piers, Prokop, Daniel   +5 more
core  

The International Competitiveness Indexes and the Structural Reforms in Japan*

Управленческие науки, 2017
The Purpose of the article is to determine the directions of the optimization of national efforts to overcome the structural problems of Russia to transit to the Industry 4.0 economic order taking into consideration the Japanese experience accumulated in
E. L. Moreva
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

INTERRELATIONS BETWEEN ECONOMIC FREEDOM, KNOWLEDGE ECONOMY AND GLOBAL COMPETITIVENESS – COMPARATIVE ANALYSIS ROMANIA AND EU AVERAGE [PDF]

Economic Freedom, Knowledge Economy and Global Competitiveness are three of the many and very different dimensions which characterize the level of a country’s performance.
Herciu Mihaela, Ogrean Claudia
core  

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source