Results 81 to 90 of about 6,438,675 (354)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Development of a stream DTM generation method using vegetation and morphology composite filters with SfM point clouds

Scientific Reports
Developing method for generating accurate Digital Terrain Model (DTM) of streams is necessary due to the limitations of traditional field survey methods, which are time-consuming and costly and do not provide continuous data.
Hyeokjin Lee, Jaejun Gou, Jinseok Park, Seongju Jang, Inhong Song   +4 more
doaj   +1 more source

Wide-Angle Image Distortion Correction and Embedded Stitching System Design Based on Swin Transformer

Applied Sciences
Wide-angle images often suffer from severe radial distortion, compromising geometric accuracy and challenging image correction and real-time stitching, especially in resource-constrained embedded environments.
Shiwen Lai, Zuling Cheng, Wencui Zhang, Maowei Chen   +3 more
doaj   +1 more source

Flood susceptibility mapping of Kathmandu metropolitan city using GIS-based multi-criteria decision analysis

Ecological Indicators, 2023
Floods are among the most severe hazards around the world triggered by climate change, threatening environmental sustainability, economies, and ecological cycles and damaging infrastructure and causing loss of lives.
Deepak Chaulagain, Parshu Ram Rimal, Same Noel Ngando, Benyoh Emmanuel Kigha Nsafon, Dongjun Suh, Jeung-Soo Huh   +5 more
doaj   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source

Comprehensive Review of Building Energy Management Models: Grid-Interactive Efficient Building Perspective

Energies
Energy management models for buildings have been designed primarily to reduce energy costs and improve efficiency. However, the focus has recently shifted to GEBs with a view toward balancing energy supply and demand while enhancing system flexibility ...
Anujin Bayasgalan, Yoo Shin Park, Seak Bai Koh, Sung-Yong Son   +3 more
doaj   +1 more source

Globalization and Contemporary Fertility Convergence [PDF]

Social Forces, 2017
The rise of the global network of nation-states has precipitated social transformations throughout the world. This article examines the role of political and economic globalization in driving fertility convergence across countries between 1965 and 2009.
openaire   +3 more sources

TESTING CONVERGENCE FOR GLOBAL ACCRETION DISKS [PDF]

The Astrophysical Journal, 2013
To appear in the Astrophysical ...
John F. Hawley, Sherwood Richers, Xiaoyue Guan, Julian H. Krolik   +3 more
openaire   +3 more sources

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

On convergence to the global optima

, 2021
We show that there is no general algorithm which finds a sequence of points with finite-precision converging computably to the global optima of any continuous function.
openaire   +2 more sources