Results 61 to 70 of about 225,788 (313)

Evaluation of fish habitat suitability based on stream hydrodynamics and water quality using SWAT and HEC-RAS linked simulation

Scientific Reports
The objective of this study was to evaluate fish habitat suitability by simulating hydrodynamic and water quality factors using SWAT and HEC-RAS linked simulation considering time-series analysis.
Jinseok Park, Seongju Jang, Hyeokjin Lee, Jaejun Gou, Inhong Song   +4 more
doaj   +1 more source

Rehydration before Application Improves Functional Properties of Lyophilized Lactiplantibacillus plantarum HAC03

Microorganisms, 2021
Preservation of probiotics by lyophilization is considered a method of choice for developing stable products. However, both direct consumption and reconstitution of dehydrated probiotic preparations before application “compromise” the survival and ...
Karina Arellano-Ayala, Juhwan Lim, Subin Yeo, Jorge Enrique Vazquez Bucheli, Svetoslav Dimitrov Todorov, Yosep Ji, Wilhelm Heinrich Holzapfel   +6 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Enhancing attention and emotion regulation in children with ADHD through AR digital picture books: a structural equation modeling approach

Frontiers in Psychology
This study investigates the effectiveness of augmented reality (AR) digital picture books in improving attention and emotional regulation among children with Attention Deficit Hyperactivity Disorder (ADHD).
Rongming Yang, Weibo Sun, Xinwei Liu, Yuanfang Cao   +3 more
doaj   +1 more source

The Influence of Human Factors in Flight Training

Hanggong uju uihakoeji, 2023
Purpose: Most aviation accidents are caused by human factors, and in recent years in Korea, human factors have been identified as the cause of 70% of aviation accidents.
Hui-Jin Kim, Jin-Kook Choi
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Development of a stream DTM generation method using vegetation and morphology composite filters with SfM point clouds

Scientific Reports
Developing method for generating accurate Digital Terrain Model (DTM) of streams is necessary due to the limitations of traditional field survey methods, which are time-consuming and costly and do not provide continuous data.
Hyeokjin Lee, Jaejun Gou, Jinseok Park, Seongju Jang, Inhong Song   +4 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Development of a stream DTM generation methodology using UAV-based SfM and LiDAR point cloud

Scientific Reports
Filtering ground points and generating accurate Digital Terrain Models (DTMs) are crucial for hydrological and ecological modeling in riverine environments.
Jaejun Gou, Hyeokjin Lee, Jinseok Park, Seongju Jang, Nakyung Lee, Inhong Song   +5 more
doaj   +1 more source