Results 51 to 60 of about 1,236,686 (282)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Rehydration before Application Improves Functional Properties of Lyophilized Lactiplantibacillus plantarum HAC03

Microorganisms, 2021
Preservation of probiotics by lyophilization is considered a method of choice for developing stable products. However, both direct consumption and reconstitution of dehydrated probiotic preparations before application “compromise” the survival and ...
Karina Arellano-Ayala, Juhwan Lim, Subin Yeo, Jorge Enrique Vazquez Bucheli, Svetoslav Dimitrov Todorov, Yosep Ji, Wilhelm Heinrich Holzapfel   +6 more
doaj   +1 more source

Global convergence of splitting methods for nonconvex composite optimization

, 2015
We consider the problem of minimizing the sum of a smooth function $h$ with a bounded Hessian, and a nonsmooth function. We assume that the latter function is a composition of a proper closed function $P$ and a surjective linear map $\cal M$, with the ...
Li, Guoyin, Pong, Ting Kei
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Evaluation of fish habitat suitability based on stream hydrodynamics and water quality using SWAT and HEC-RAS linked simulation

Scientific Reports
The objective of this study was to evaluate fish habitat suitability by simulating hydrodynamic and water quality factors using SWAT and HEC-RAS linked simulation considering time-series analysis.
Jinseok Park, Seongju Jang, Hyeokjin Lee, Jaejun Gou, Inhong Song   +4 more
doaj   +1 more source

Bacteriocinogenic Enterococcus casseliflavus Isolated from Fresh Guava Fruit (Psidium guajava): Characterization of Bacteriocin ST192Gu and Some Aspects of Its Mode of Action on Listeria spp. and Enterococcus spp.

Fermentation, 2023
Strain ST182Gu, isolated from fresh guava fruit, was identified as Enterococcus casseliflavus on the basis of biochemical tests, sugar fermentation reactions (API20Strip), PCR with genus-specific primers, and 16S rRNA sequencing.
Svetoslav Dimitrov Todorov, Wilhelm Heinrich Holzapfel, John Robert Tagg   +2 more
doaj   +1 more source

The Global Convergence of Global Settlements [PDF]

Kansas Law Review, 2017
This article was written for a symposium celebrating the fiftieth anniversary of the modern class action. It argues that a global trend in mass litigation is emerging. Spurred by “victim-centered” justice movements in criminal and administrative law, the United States increasingly relies on public actors — state attorneys general, federal prosecutors ...
openaire   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Enhancing attention and emotion regulation in children with ADHD through AR digital picture books: a structural equation modeling approach

Frontiers in Psychology
This study investigates the effectiveness of augmented reality (AR) digital picture books in improving attention and emotional regulation among children with Attention Deficit Hyperactivity Disorder (ADHD).
Rongming Yang, Weibo Sun, Xinwei Liu, Yuanfang Cao   +3 more
doaj   +1 more source

The Influence of Human Factors in Flight Training

Hanggong uju uihakoeji, 2023
Purpose: Most aviation accidents are caused by human factors, and in recent years in Korea, human factors have been identified as the cause of 70% of aviation accidents.
Hui-Jin Kim, Jin-Kook Choi
doaj   +1 more source