Results 31 to 40 of about 5,959,101 (252)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The present chapter tries to examine the trend of productivity growth and the process of convergence of productivity among the countries within three blocks viz., ASEAN, APEC and SAARC, using the datacompiled by R. Summers and A.
Yılmaz, D., Ertürk, E., Çetin, I.
core +1 more source
French corporate governance in the new global economy: mechanisms of change and hybridisation within models of capitalism [PDF]
This article analyses the implications of the internationalisation of capital markets, and the influx of Anglo-Saxon institutional investors, for the French model of capitalism.
Clift, Ben, Ben Clift
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Temu has become a prominent cross-border e-commerce platform combining low-price positioning, personalized recommendations, and mobile-based shopping, but its platform features may create both perceived value and digital risk concerns.
Xiaoyu Zhang, Luning Tong, Maowei Chen
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Metaverse? No, thanks! Exploring the mechanisms behind Generation Z’s resistance behavior
The metaverse is progressively advancing toward broad application in real-world scenarios. However, as a key driving force of today’s digital economy, Generation Z has not demonstrated sufficient enthusiasm for participation.
Ning Ding +4 more
doaj +1 more source
Enterococcus spp., known for their wide ecological distribution, have been associated with various fermented food products of plant and animal origin.
Joanna Ivy Irorita Fugaban +2 more
doaj +1 more source
Continuing Global Fertility Convergence [PDF]
This study reexamines fertility convergence by extending Dorius (2008), who explored global fertility convergence with quinquennial data from 1955–2005.
Nakagaki, Yoko, 1481
core +1 more source

