Results 81 to 90 of about 227,885 (313)

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

A Study on Non-Compliance with Standard Phraseology and Communication Errors in Pilot-Controller Communication

open access: yesHanggong uju uihakoeji, 2023
Purpose: In this study, in order to examine the correlation between non-compliance with standard phraseology and communication errors in pilot-controller communications, investigated the perception of standard phraseology.
Ho-Jae Yun, Jin-Kook Choi
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

A multi-modal approach for recognizing fake news and influential nodes in spreading them using deep learning and network analysis

open access: yesScientific Reports
Rumors may spread swiftly and cause a lot of harm on social media. Finding the main nodes that fuel rumor’s spread is necessary to lessen their impact. This study proposes a new technique that combines deep learning with graph-based clustering techniques
Weiliang Zhang   +2 more
doaj   +1 more source

Unraveling the Dynamics of Digital Inclusion: Exploring the Third-Level Digital Divide Among Older Adults in China

open access: yesApplied Sciences
The COVID-19 pandemic catalyzed engagement in photographic activities among older adults, yet research remains limited on how these activities promote digital inclusion within the context of the third-level digital divide.
Qian Cheng, Maowei Chen
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Lightweight Multi-Task Learning Method for System Log Anomaly Detection

open access: yesIEEE Access
Log anomaly detection is a crucial task in monitoring IT systems along with metrics and traces. An anomaly could be detected by either one of two types of logs: individual logs or log sequences.
Tuan-Anh Pham, Jong-Hoon Lee
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Convergence clubs, the euro-area rank and the relationship between banking and real convergence [PDF]

open access: yes
This paper analyses banking convergence, measured through the ratios of deposits and loans to GDP, across 65 countries, compares it with per capita income convergence, and tests its effect on real convergence.
Massimiliano Affinito
core  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

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