Results 91 to 100 of about 2,707,305 (304)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

China`s «One Belt – One Road» Initiative and Strategic Challenges to the USA

open access: yesАмериканська історія і політика, 2017
At first glance the basis of the Initiative “One Belt – One Road” voiced by Chinese leader Xi Jinping is composed of geo-economics’ vectors. Cooperation within the framework of the two silk routes will be complemented by social and political dynamics ...
Makar Taran
doaj  

Will Donald Trump Change the Paradigm of Global Development?

open access: yesPolish Political Science Yearbook
The aim of this article is to assess the extent to which Donald Trump’s economic program could lead to the formation of a new paradigm for global economic development, built around protectionism. The analysis is based on the president’s election platform
Witold Orłowski
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Aid for Trade: The Inter-American Development Bank\u27s Experience in Latin America and the Caribbean [PDF]

open access: yes, 2006
This document summarizes the Inter-American Development Bank (IDB) experience as one of the main sources of multilateral development financing in Latin America and the Caribbean.
Inter-American Development Bank
core   +1 more source

The Royal We and the Good Life

open access: yesExchanges
This Critical Reflection problematizes the notion of a collective ‘we’ who cannot seem to achieve sustainability. The fiction of this notion creates a split in that we, between the simultaneous existence of a ‘comfortable we’ and an unmarked collective ...
Courtney Work
doaj   +1 more source

New Goals of Sustainable Future [PDF]

open access: yesФилософия и космология, 2017
This article investigates the process of transition from the Millennium Development Goals to Sustainable Development Goals (SDGs). The authors have set an objective to demonstrate that SD as a future form of development of civilization from the very ...
Arkady Ursul   +2 more
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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