Results 101 to 110 of about 2,426,099 (326)

Boundedness and stabilization in a quasilinear chemotaxis model with nonlocal growth term and indirect signal production

open access: yesCommunications in Analysis and Mechanics
In this paper, we study the following fully parabolic chemotaxis system with nonlocal growth and indirect signal production: \begin{document}$ \begin{equation*} \left\{ \begin{array}{@{}l@{\quad}l} u_{t} = \nabla\cdot( D(u)\nabla u)-\nabla\cdot(u ...
Min Jiang, Dandan Liu, Rengang Huang
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Research on the Properties of Solutions to Fourth-Order Pseudo-Parabolic Equations with Nonlocal Sources

open access: yesMathematics
This paper investigates the initial-boundary value problem for a fourth-order pseudo-parabolic equation with a nonlocal source: ut+Δ2u−Δut=uq−1u−1Ω∫Ωuq−1udx.
Chunxiao Yang, Wanqing Li
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Global Existence, General Decay, and Blow Up of the Solution to the Coupled p-Biharmonic Equation of Hyperbolic Type with Degenerate Damping Terms

open access: yesMathematics
In this work, we study a nonlinear system of p-Biharmonic hyperbolic equations with degenerate damping and source terms in a bounded domain. Under appropriate assumptions on the initial data and the damping terms, we establish the global existence of ...
Nouri Boumaza   +3 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy