Results 111 to 120 of about 327,801 (268)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Global Existence and Uniqueness of Bohmian Trajectories

open access: yes, 1996
It is shown that Bohmian mechanics is internally consistent in the sense that the equations of motion typically have global solutions despite the fact that the velocity field is singular at the nodes of the wave function and at other points. This result is fundamental for the derivation of the quantum formalism.
openaire   +2 more sources

Global Existence and Exponential Stability of Convection

open access: yesJournal of Mathematical Analysis and Applications, 1995
The interior convection in the Boussinesq approximation is studied for a bounded domain \(\Omega\subset \mathbb{R}^3\), occupied by an incompressible, viscous fluid, with a smooth boundary \(\Gamma\). It is studied the gravitational convection when the fluid is heated at a part \(\Gamma_0\subset\Gamma\) of the boundary.
openaire   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Global Existence and Decay Estimates for a Viscoelastic Petrovsky–Kirchhoff-Type Equation with a Delay Term

open access: yesAxioms
In this paper, we consider a viscoelastic Kirchhoff equation with a delay term in the internal feedback. By using the Faedo–Galerkin approximation method, we prove the well posedness of the global solutions.
Noureddine Sebih   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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