Results 101 to 110 of about 327,801 (268)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Global existence for semilinear parabolic systems.
Journal für die reine und angewandte Mathematik (Crelles Journal), 1985 This paper studies the problem of global existence for strongly coupled semilinear parabolic systems of arbitrary even order under linear time- dependent boundary conditions. In particular it is shown that there exist classical global solutions provided the nonlinearity satisfies appropriate polynomial growth restrictions and a priori estimates in some
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Existence of a Global Solution for a Viscoelastic System
Journal of Mathematical Analysis and Applications, 1998 The author considers the Cauchy problem for the viscoelastic system \[ v_t- u_x= 0,\quad u_t- f(v)_x+ ku= u_{xx} \] without the restriction that the initial data approach constants at infinity. Existence of unique classical solution is proved, including a priori estimates.
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
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Global Existence and Nonexistence in a System of Petrovsky
Journal of Mathematical Analysis and Applications, 2002 The author considers the problem \[ \begin{cases} u_{tt}+\Delta^2u+au_t|u_t|^{m-2}=bu|u|^{p-2}, &x\in \Omega\;\text{ and } t>0,\\ u(x,t)=\partial_\nu u(x,t)=0, &x\in \partial\Omega\;\text{ and } t\geq 0,\\ u(x,0)=\phi(x), u_t(x,0)=\psi(x), &x\in\Omega,\end{cases}\tag{1} \] where \(\Omega\) is a bounded domain of \({\mathbb{R}}^n\) with smooth boundary \
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