Results 101 to 110 of about 6,658,638 (311)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Asymptotic Analysis and Blow-Up of Solution for a q-Kirchhoff-Type Equation with Nonlinear Boundary Damping and Source Terms with Variable Exponents

Mathematics
In this study, we examine a q-Kirchhoff-type equation defined on a bounded domain, incorporating nonlinear boundary damping and source terms with variable exponents. Assuming appropriate conditions on the initial data and the variable exponent functions,
Nouri Boumaza, Billel Gheraibia, Zayd Hajjej, Hongwei Zhang, Said Mesloub   +4 more
doaj   +1 more source

On the Global Existence and Boundedness of Solutions of a Certain Integro-Vector Differential Equation of Second Order

Journal of Mathematical and Fundamental Sciences, 2018
In this paper, we consider a nonlinear integro-vector differential equation of the second order. We establish sufficient conditions that guarantee the global existence and boundedness of solutions of the equation considered. The method of proof involves
Cemil Tunc, Timur Ayhan
doaj   +1 more source

U.S. Global Change Research Program Program Overview: USGCRP At A Glance [PDF]

This fact sheet presents an overview of the U.S.
U.S. Global Change Research Program
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Local Existence and Regularity of Mild Solutions for Hadamard Fractional Semilinear Integro-Differential Equations with Compact Semigroups

Axioms
We investigate the local well-posedness of semilinear fractional integro-differential equations in Banach spaces with the Hadamard fractional derivative.
Ahmad Al-Omari, Mohammad H. M. Rashid
doaj   +1 more source

Global existence of solutions for the thermoelasticBresse system

Communications on Pure and Applied Analysis, 2014
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Qin, Yuming, Yang, Xinguang, Ma, Zhiyong
openaire   +2 more sources

Global Religious Terrorism a Troubling Phenomenon

, 2019
Terrorism is an ancient phenomenon as it comes from classical Antiquity However its global version only started in the last decades of the 19th century after the fall of Paris Commune and the murder of the Russian tzar Alexander the second Global ...
José F. Pinto
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Existence of global solutions to reaction-diffusion systems with nonhomogeneous boundary conditions via a Lyapunov functional

Electronic Journal of Differential Equations, 2002
Most publications on reaction-diffusion systems of $m$ components ($mgeq 2$) impose $m$ inequalities to the reaction terms, to prove existence of global solutions (see Martin and Pierre [10 ] and Hollis [4]).
Said Kouachi
doaj