Results 181 to 190 of about 8,147,434 (373)

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

open access: yesFEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang   +6 more
wiley   +1 more source

Energy decay for wave equations of phi-Laplacian type with weakly nonlinear dissipation

open access: yesElectronic Journal of Differential Equations, 2008
In this paper, first we prove the existence of global solutions in Sobolev spaces for the initial boundary value problem of the wave equation of $phi$-Laplacian with a general dissipation of the form $$ (|u'|^{l-2}u')'-Delta_{phi}u+sigma(t) g(u')=0 ...
Aissa Guesmia, Abbes Benaissa
doaj  

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

open access: yesFEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr   +5 more
wiley   +1 more source

Existence of global solutions to reaction-diffusion systems via a Lyapunov functional

open access: yesElectronic Journal of Differential Equations, 2001
The purpose of this paper is to construct polynomial functionals (according to solutions of the coupled reaction-diffusion equations) which give $L^{p}$-bounds for solutions.
Said Kouachi
doaj  

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

open access: yesFEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

Existence of solutions to nonlinear parabolic problems with delay

open access: yesElectronic Journal of Differential Equations, 2004
We prove the existence and uniqueness of global solutions to semilinear parabolic equations with a nonlinear delay term. We study these problems in the whole space $mathbb{R}^n$, obtain classic solutions, and give a mass decay result of the solution.
Deliang Hsu
doaj  

Menthol‐like cooling compounds, including (R)‐(‐)‐carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K

open access: yesFEBS Open Bio, EarlyView.
We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Miyuu Saito, Takumi Misaka
wiley   +1 more source

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