Results 141 to 150 of about 1,195,865 (301)

Capitalising (on) industrial epidemics: examining the influence of the ‘Big Three’ asset managers on corporate governance in key health-harming commodity industries

Globalization and Health
Background In recent decades, the Big Three asset managers (BlackRock, Vanguard, State Street) have emerged to be among the top shareholders in thousands of listed companies worldwide.
Benjamin Wood, Scott Slater, Sharon Friel, Ashley Schram, Nicholas Frank, Gary Sacks   +5 more
doaj   +1 more source

Opinion: Toward inclusive global governance of human genome editing. [PDF]

Proc Natl Acad Sci U S A, 2021
Yu H, Xue L, Barrangou R, Chen S, Huang Y.   +4 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Digitising biopiracy? The global governance of plant genetic resources in the age of digital sequencing information. [PDF]

Third World Q, 2022
Nehring R.
europepmc   +1 more source

Global Governance

, 2006
Die Sozialwissenschaften reden ganz selbstverständlich von Global Governance, obwohl es (noch) keinen Weltstaat und auch keine Weltregierung gibt. Dennoch hat sich eine Weltgesellschaft in nuce herausgebildet, die eigene, globale Formen der Regierung und der Selbststeuerung anstelle staatszentrierter politischer Steuerung hervorbringt.
openaire   +3 more sources

Global environmental governance: the challenge of accountability [PDF]

, 2010
This repository item contains a single issue of Sustainable Development Insights, a series of short policy essays that began publishing in 2008 by the Boston University Frederick S. Pardee Center for the Study of the Longer-Range Future. The series seeks
Halle, Mark, Najam, Adil
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Challenges and Approaches of the Global Governance of Public Health Under COVID-19. [PDF]

Front Public Health, 2021
Zhang H.
europepmc   +1 more source

Keynote Reflections: The Public Governance Duty [PDF]

, 2015
Firms must take ever greater risks to try to innovate and create value in our increasingly competitive and complex global economy. Corporate governance law generally delegates control over excessive risk-taking to the firm’s investors, principally its ...
Schwarcz, Steven L.
core   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source