Results 201 to 210 of about 2,288,892 (269)

Same actors, same processes, same outcomes: Global health architecture reform or restoration? [PDF]

PLOS Glob Public Health
Kantiana ID, Alpeza F, Bandara S, Cook AR, Rahman-Shepherd A.   +4 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Beyond paper walls: From diagnosis to action on visa inequities in global health. [PDF]

PLOS Glob Public Health
Novak S, Venzor Strader A, Gbagornah P, Orrego Villegas S.   +3 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Pacific pathways for inclusive global health. [PDF]

Lancet Reg Health West Pac
Bhatta S, Pant N.
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

The International Health Regulations and the imperative to strengthen global health: the case of Brazil. [PDF]

Rev Soc Bras Med Trop
Garcia MHO, Maciel EL, Lima NT.
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

The global health case report. [PDF]

BMJ Glob Health
Patel T, Douthit N, Mazuz K, Mwakyula I, Ramirez EL, DSouza R, Aranda Z, Guevara-Aguirre J, Rasul T, Bin S, Ismavel VA, Biswas S.   +11 more
europepmc   +1 more source

Agentic AI in global health equity for high altitude populations. [PDF]

NPJ Digit Med
Shi P, Ren T, Xie Y, Gichoya JW, Wong TY, Ji X, Wang N, Yuan W.   +7 more
europepmc   +1 more source