Results 51 to 60 of about 5,735,852 (363)

The U.S. Global Health Initiative: Key Issues [PDF]

open access: yes, 2010
Explores issues of GHI governance, funding allocation, impact measurement, ownership by recipient countries, international partnerships, implementing focus on women and girls, health systems strengthening, and coordination with foreign aid reform ...

core  

Artificial Intelligence for Global Health: Learning From a Decade of Digital Transformation in Health Care [PDF]

open access: yes, 2020
The health needs of those living in resource-limited settings are a vastly overlooked and understudied area in the intersection of machine learning (ML) and health care.
Gichoya, Judy Wawira   +2 more
core   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Global IDEA [PDF]

open access: yes, 2005
Five members of the Global IDEA Scientific Advisory Committee respond to Dr. Moore and colleagues: Global IDEA Scientific Advisory Committee.
Buxton, MJ, Hanney, S
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

A bright future in typhoid vaccines

open access: yesThe Lancet Global Health, 2021
The Lancet Global Health
doaj   +1 more source

Call for emergency action to limit global temperature increases, restore biodiversity and protect health [PDF]

open access: hybrid, 2021
Lukoye Atwoli   +18 more
openalex   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The \u3cem\u3eLancet\u3c/em\u3e Commission on Global Health Law: The Transformative Power of Law to Advance the Right to Health [PDF]

open access: yes, 2019
A new report by The Lancet-O’Neill-Georgetown University Commission on Global Health and the Law shows how law can fulfill the global pledge of the human right to health, while “leaving no one behind.” I call this “global health with justice.” We need ...
Gostin, Lawrence O.
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

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