Results 71 to 80 of about 5,439,025 (359)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

The U.S. Global Health Initiative: Key Issues [PDF]

open access: yes, 2010
Explores issues of GHI governance, funding allocation, impact measurement, ownership by recipient countries, international partnerships, implementing focus on women and girls, health systems strengthening, and coordination with foreign aid reform ...

core  

Global public health training in the UK: preparing for the future.

open access: yes, 2011
BACKGROUND: Many major public health issues today are not confined by national boundaries. However, the global public health workforce appears unprepared to confront the challenges posed by globalization.
Hall, Jennifer A   +2 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

The \u3cem\u3eLancet\u3c/em\u3e Commission on Global Health Law: The Transformative Power of Law to Advance the Right to Health [PDF]

open access: yes, 2019
A new report by The Lancet-O’Neill-Georgetown University Commission on Global Health and the Law shows how law can fulfill the global pledge of the human right to health, while “leaving no one behind.” I call this “global health with justice.” We need ...
Gostin, Lawrence O.
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

The Global Health Watch

open access: yesPLoS Medicine, 2004
Why three non-governmental organizations are launching an alternative to the World Health ...
David McCoy   +3 more
openaire   +5 more sources

Publisher Correction to: Global Health Research and Policy, volume 4

open access: yesGlobal Health Research and Policy, 2019
An error occurred during the publication of a number of articles Global Health Research and Policy. Several articles were published in volume 4 with a duplicate citation number.
Global Health Research and Policy
doaj   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

The U.S. Commitment to Global Health: Recommendations for the New Administration [PDF]

open access: yes, 2008
Outlines the need for making a commitment to improving global health an integral part of U.S. foreign policy. Suggestions include creating a White House Interagency Committee on Global Health and directing more funds to chronic disease ...

core  

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